Hai cercato: H-D-Phe(3,5-DiF)-OH

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Boc-N-Me-Dl-Val-Oh 97%

Fornitore: Apollo Scientific

Descrizione: Boc-N-Me-Dl-Val-Oh 97%

Fmoc-L-Lys(N3)-OH ≥98.0% (by HPLC, titration analysis)

Codice catalogo: (TCIAA3023-250MG)

Fornitore: TCI

Codice articolo fornitore: A3023-250MG

Codice articolo locale: TCIAA3023-250MG

Descrizione: Fmoc-L-Lys(N3)-OH ≥98.0% (by HPLC, titration analysis)

UOM: 1 * 250 mg

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Anti-CAB39 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-3636R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-3636R-A350

Codice articolo locale: BOSSBS-3636R-A350

Descrizione: Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.

UOM: 1 * 100 µl

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Non disponibile confezione

Anti-CAB39 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-3636R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-3636R-A488

Codice articolo locale: BOSSBS-3636R-A488

UOM: 1 * 100 µl

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Etanolammina, Supelco®

Codice catalogo: (00278-5ML-F)

Fornitore: Merck

Codice articolo fornitore: 00278-5ML-F

Codice articolo locale: SUPL00278-5ML-F

Descrizione: Etanolammina, Supelco®

UOM: 1 * 5 mL

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Anti-PSMA7 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-9356R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-9356R-A555

Codice articolo locale: BOSSBS-9356R-A555

Descrizione: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

UOM: 1 * 100 µl

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