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Image Unavailable-BOSSBS-9125R-A680

Anti-COPS2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descrizione: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Codice catalogo: BOSSBS-9125R-A680
UOM: 1 * 100 µl
Codice articolo fornitore: BS-9125R-A680
Codice articolo locale: BOSSBS-9125R-A680
Fornitore: Bioss
Image Unavailable-BOSSBS-9126R-A647

Anti-GPS1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Descrizione: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.
Codice catalogo: BOSSBS-9126R-A647
UOM: 1 * 100 µl
Codice articolo fornitore: BS-9126R-A647
Codice articolo locale: BOSSBS-9126R-A647
Fornitore: Bioss
Image Unavailable-40718.MD

Zinc tert-butoxide

Descrizione: Zinc tert-butoxide
Codice catalogo: 40718.MD
UOM: 1 * 250 mg
Codice articolo fornitore: 40718.MD
Codice articolo locale: ALFA40718.MD
Fornitore: Thermo Fisher Scientific

MSDS Certificati


Image Unavailable-APOSPC5876-5G

4-(tert-Butoxy)benzotrifluoride 97%

Descrizione: 4-(tert-Butoxy)benzotrifluoride 97%
Codice catalogo: APOSPC5876-5G
UOM: 1 * 5 g
Codice articolo fornitore: PC5876-5G
Codice articolo locale: APOSPC5876-5G
Fornitore: Apollo Scientific
Image Unavailable-APOSOR930175-1G

6-tert-Butylnicotinic acid 98%

Descrizione: 6-tert-Butylnicotinic acid 98%
Codice catalogo: APOSOR930175-1G
UOM: 1 * 1 g
Codice articolo fornitore: OR930175-1G
Codice articolo locale: APOSOR930175-1G
Fornitore: Apollo Scientific
Image Unavailable-75918-50MG

Supelco® TraceCERT® Organic Reference Standard, 2,6-Di-tert-butyl-4-methylphenol

Descrizione: Organic Standard, 2,6-Di-tert-butyl-4-methylphenol
Codice catalogo: 75918-50MG
UOM: 1 * 50 mg
Codice articolo fornitore: 75918-50MG
Codice articolo locale: SUPL75918-50MG
Fornitore: Merck

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Image Unavailable-APOSOR40497-1G

2-tert-Butylbenzoic acid

Descrizione: 2-tert-Butylbenzoic acid
Codice catalogo: APOSOR40497-1G
UOM: 1 * 1 g
Codice articolo fornitore: OR40497-1G
Codice articolo locale: APOSOR40497-1G
Fornitore: Apollo Scientific
Image Unavailable-BOSSBS-6634R-CY5

Anti-XPC Rabbit Polyclonal Antibody (Cy5®)

Descrizione: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Codice catalogo: BOSSBS-6634R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-6634R-CY5
Codice articolo locale: BOSSBS-6634R-CY5
Fornitore: Bioss
Image Unavailable-BOSSBS-6634R-A647

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Descrizione: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Codice catalogo: BOSSBS-6634R-A647
UOM: 1 * 100 µl
Codice articolo fornitore: BS-6634R-A647
Codice articolo locale: BOSSBS-6634R-A647
Fornitore: Bioss
Image Unavailable-APOSOR923989-500G

4-tert-Butylcyclohexanone 98%

Descrizione: 4-tert-Butylcyclohexanone 98%
Codice catalogo: APOSOR923989-500G
UOM: 1 * 500 g
Codice articolo fornitore: OR923989-500G
Codice articolo locale: APOSOR923989-500G
Fornitore: Apollo Scientific
Image Unavailable-APOSOR2417-1G

tert-Butyl-3-aminobenzoate

Descrizione: tert-Butyl-3-aminobenzoate
Codice catalogo: APOSOR2417-1G
UOM: 1 * 1 g
Codice articolo fornitore: OR2417-1G
Codice articolo locale: APOSOR2417-1G
Fornitore: Apollo Scientific
Image Unavailable-BOSSBS-1597R

Anti-Parafibromin Rabbit Polyclonal Antibody

Descrizione: The HRPT2 gene product, parafibromin, is a tumor suppressor protein that is part of the human Paf1 complex. The yeast counterpart to this complex is part of the RNA polymerase II complex as well, and is important for histone modification and connections to posttranscriptional events. Human parafibromin also associates with the RNA polymerase II large subunit.
Codice catalogo: BOSSBS-1597R
UOM: 1 * 100 µl
Codice articolo fornitore: BS-1597R
Codice articolo locale: BOSSBS-1597R
Fornitore: Bioss
Product Image-NOVUNB100-914

Anti-Mre11-Rad50-NBS1 Complex Rabbit Antibody

Descrizione: Rabbit Mre11-Rad50-NBS1 Complex Antibody Pack. Tested Reactivity: Human, Mouse.
Codice catalogo: NOVUNB100-914
UOM: 1 * 3 Vial
Codice articolo fornitore: NB100-914
Codice articolo locale: NOVUNB100-914
Fornitore: Novus Biologicals
Product Image-430921000.

tert-Butylchlorodiphenylsilane 98%, AcroSeal®

Descrizione: tert-Butylchlorodiphenylsilane 98%, AcroSeal®
Codice catalogo: 430921000.
UOM: 1 * 100 mL
Codice articolo fornitore: 430921000
Codice articolo locale: ACRO430921000
Fornitore: Thermo Fisher Scientific

MSDS


Image Unavailable-L13611.14

2-(4-tert-Butylphenyl)ethanol 96%

Descrizione: 2-(4-tert-Butylphenyl)ethanol 96%
Codice catalogo: L13611.14
UOM: 1 * 25 g
Codice articolo fornitore: L13611.14
Codice articolo locale: ALFAL13611.14
Fornitore: Thermo Fisher Scientific

MSDS Certificati


Image Unavailable-A15740.06

4-tert-Butylbenzaldehyde ≥97%

Descrizione: 4-tert-Butylbenzaldehyde ≥97%
Codice catalogo: A15740.06
UOM: 1 * 5 g
Codice articolo fornitore: A15740.06
Codice articolo locale: ALFAA15740.06
Fornitore: Thermo Fisher Scientific

MSDS Certificati


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