Hai cercato: Shenandoah Biotechnology

Fornitore: Shenandoah Biotechnology

Descrizione: Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation.

Fornitore: Shenandoah Biotechnology

Descrizione: Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12).

Fornitore: Shenandoah Biotechnology

Descrizione: Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10Rbeta chains. IL-22 is a potent mediator of cellular inflammatory responses and wound healing.

Fornitore: Shenandoah Biotechnology

Descrizione: Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation.

Fornitore: Shenandoah Biotechnology

Descrizione: Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets.

Fornitore: Shenandoah Biotechnology

Descrizione: Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells.

Fornitore: Shenandoah Biotechnology

Descrizione: Galectin-1 belongs to the lectin family of carbohydrate binding proteins and binds glycans as both as a monomer and a homodimer.

Fornitore: Shenandoah Biotechnology

Descrizione: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS).

Fornitore: Shenandoah Biotechnology

Descrizione: Growth hormone is an important mitogenic growth factor that is synthesised, stored, and secreted by somatotropic cells of the anterior pituitary gland. They stimulates growth, cell reproduction, and cell regeneration.

Fornitore: Shenandoah Biotechnology

Descrizione: Tumor necrosis factor alpha (TNFα) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNFα signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells.

Fornitore: Shenandoah Biotechnology

Descrizione: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells.

Fornitore: Shenandoah Biotechnology

Descrizione: Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.

Fornitore: Shenandoah Biotechnology

Descrizione: Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) expression in monocytes, and promotes type 2 T helper (Th2) cell-mediated immune responses.

Fornitore: Shenandoah Biotechnology

Descrizione: Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes.

Fornitore: Shenandoah Biotechnology

Descrizione: Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling.

Fornitore: Shenandoah Biotechnology

Descrizione: Macrophage inflammatory protein 2 (MIP-2), also known as CXCL2, is a small cytokine that is secreted by monocytes and neutrophils at sites of inflammation. MIP-2 functions through the chemokine receptor CXCR2 to act as a chemotactic agent for leukocytes and hematopoietic cells.