Hai cercato: ENZO LIFE SCIENCES

Codice catalogo: (ENZOADISAB100J)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ADISAB100J

Codice articolo locale: ENZOADISAB100J

Descrizione: Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay Designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.

UOM: 1 * 1 mL

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Codice catalogo: (ENZOADISOD101E)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ADISOD101E

Codice articolo locale: ENZOADISOD101E

Descrizione: SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).

UOM: 1 * 100 µG

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Fornitore: ENZO LIFE SCIENCES

Descrizione: The 70 kDa heat shock protein Hsp70 belongs to the Hsp70 family of highly-related protein isoforms ranging in size from 66 kDa to 78 kDa. Hsc70 shares close biochemical and biological ties to Hsp70, and also belongs to the Hsp70 family. These proteins include cognate members found within major intracellular compartments and highly inducible isoforms predominantly cytoplasmic or nuclear in distribution. Members of the Hsp70 family function as molecular chaperones involved in such cellular functions as protein folding, transport, maturation and degradation, operating in an ATP-dependent manner. The molecular chaperones of the Hsp70 family recognize and bind to nascent polypeptide chains or partially folded intermediates of proteins, preventing their aggregation and misfolding, and the binding of ATP triggers a critical conformational change leading to the release of the bound substrate protein. Data demonstrates that with a ubiquitin-like domain at its amino terminus and its association with the 26S proteosome in HeLa cells, Bag-1 modulates the chaperone activity of Hsc70 and Hsp70. These findings reveal Bag-1's role as a physical link between the Hsc70/Hsp70 chaperone system and the proteasome. Experimental data also shows that the ATPase domain and the substrate-binding domain of Hsp70 (or Hsc70) cooperate to form a co-chaperone-chaperone complex with the synaptic vesicle cysteine string protein (csp), essential for normal neurotransmitter release.

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Codice catalogo: (ENZOADISPA815488E)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ADISPA815488E

Codice articolo locale: ENZOADISPA815488E

Descrizione: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

UOM: 1 * 100 µG

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Anti-HSP90B1 Rabbit Polyclonal Antibody

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Codice catalogo: (ENZOADISPA960E)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ADISPA960E

Codice articolo locale: ENZOADISPA960E

Descrizione: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

UOM: 1 * 100 µG

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in<i> E. coli</i>. Human αA-Crystallin is fused at the N-terminus to a His-tag.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in <i>E. coli</i>.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin.

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Codice catalogo: (ENZOBMLPH1060100)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLPH1060100

Codice articolo locale: ENZOBMLPH1060100

Descrizione: Activator of PKC and Akt

UOM: 1 * 100 µG

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Caspase inhibitor

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Neprilysin inhibitor

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Codice catalogo: (ENZOBMLPI1240005)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLPI1240005

Codice articolo locale: ENZOBMLPI1240005

Descrizione: Negative control for AAF-CMK

UOM: 1 * 5 mg

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Codice catalogo: (ENZOBMLSE3140100)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLSE3140100

Codice articolo locale: ENZOBMLSE3140100

Descrizione: Produced in <i>E. coli</i>. Human 14-3-3epsilon is fused at the N-terminus to a GST-tag.

UOM: 1 * 100 µG

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Codice catalogo: (ENZOBMLSE3850005)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLSE3850005

Codice articolo locale: ENZOBMLSE3850005

Descrizione: Produced in insect cells. Full length active enzyme.

UOM: 1 * 5 µG

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Codice catalogo: (ENZOBMLSE3210100)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLSE3210100

Codice articolo locale: ENZOBMLSE3210100

Descrizione: Produced in <i>E. coli</i>.

UOM: 1 * 100 µG

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