Hai cercato: ENZO LIFE SCIENCES

Fornitore: ENZO LIFE SCIENCES

Descrizione: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

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Codice catalogo: (ENZOADISPP227F)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ADISPP227F

Codice articolo locale: ENZOADISPP227F

Descrizione: Isolated from bovine eye lens.

UOM: 1 * 200 µG

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: GroEL and GroES are <i>E. coli</i> chaperonins, which are homologs of mitochondrial chaperonins Hsp60 and Hsp10. GroEL is a double toriodal assembly of 14 identical subunits which form two heptameric rings stacked back-to-back, with a cavity at each end. GroEL and its co-chaperonin GroES facilitate protein folding with an ATP-dependent mechanism.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in <i>E. coli</i>.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in <i>E. coli</i>.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in Sf21 cells.

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Codice catalogo: (ENZOALX2017521)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ALX2017521

Codice articolo locale: ENZOALX2017521

Descrizione: Produced in Drosophila Schneider 2 (S2) cells. Recombinant human matriptase-2 (aa 78-811) is fused at the C-terminus to a V5-His-tag.

UOM: 1 * 1 Vial

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in <i>E. coli</i>. Non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: Produced in <i>E. coli</i>.

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Fornitore: ENZO LIFE SCIENCES

Descrizione: PLA2 stimulatory bee venom peptide. Sequence is similar to Phospholipase A2 Activating Peptide (Prod. No. ALX-165-007). Activates PLA2 (5-fold at 10 µg/ml) in BC3H1 cells. For additional technical information see melittin (natural) (Prod. No. ALX-162-006).

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Codice catalogo: (ENZOALX200421C005)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ALX200421C005

Codice articolo locale: ENZOALX200421C005

Descrizione: MMP-8 is a glycoprotein containing complex N-linked oligosaccharides.

UOM: 1 * 5 µG

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Codice catalogo: (ENZOALX164005M001)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ALX164005M001

Codice articolo locale: ENZOALX164005M001

Descrizione: Food intake modulator

UOM: 1 * 1 mg

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Codice catalogo: (ENZOALX201034M001)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ALX201034M001

Codice articolo locale: ENZOALX201034M001

Descrizione: Produced in <i>E. coli</i>. Homologous to human serum leptin.

UOM: 1 * 1 mg

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Codice catalogo: (ENZOALX157011MC01)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: ALX157011MC01

Codice articolo locale: ENZOALX157011MC01

Descrizione: Guanylyl cyclase activator

UOM: 1 * 0,1 mg

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