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Fornitore: Spectrum Chemical
Descrizione: Magnesium citrate, anhydrous, USP is often used as a saline laxative but is also used as a food additive and dietary supplement.

Fornitore: Spectrum Chemical
Descrizione: Isopropyl myristate NF
Fornitore: Spectrum Chemical
Descrizione: Form: Powder

Fornitore: Spectrum Chemical
Descrizione: Sunset yellow FCF

Fornitore: Spectrum Chemical
Descrizione: L(+)-Cisteina

Codice catalogo: (SPCMD2948-200LTBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: D2948-200LTBL
Codice articolo locale: SPCMD2948-200LTBL
Descrizione: Dimethyl Glutarate is used in de-icing and anti-icing applications, construction and road applications, and release and binders agents.
UOM: 1 * 200 L


Codice catalogo: (SPCMA2305-50KGBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: A2305-50KGBL
Codice articolo locale: SPCMA2305-50KGBL
Descrizione: p-Aminophenol, also known as 4-Aminophenol, is a building block compound and can be used as a film developer.
UOM: 1 * 50 kg


Codice catalogo: (SPCMD2915-1LT)
Fornitore: Spectrum Chemical
Codice articolo fornitore: D2915-1LT
Codice articolo locale: SPCMD2915-1LT
Descrizione: Dibutyl Sebacate, also known as DBS, is used as a plasticizer in production of plastics. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.
UOM: 1 * 1 L


Fornitore: Spectrum Chemical
Descrizione: Butyl Alcohol, NF is primarily a solvent.

Codice catalogo: (SPCMD2049-200LTBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: D2049-200LTBL
Codice articolo locale: SPCMD2049-200LTBL
Descrizione: 1,3-Diaminopropane, also known as Trimethylenediamine, is isomeric with 1,2-diaminopropane and used in the synthesis of heterocycles. It is a simple diamine considered soluble in polar organic solvents.
UOM: 1 * 200 L


Codice catalogo: (SPCMSO170-500GM)
Fornitore: Spectrum Chemical
Codice articolo fornitore: SO170-500GM
Codice articolo locale: SPCMSO170-500GM
Descrizione: Sodium Hydroxide, Pellets, NF is used as a pH adjusting agent.
UOM: 1 * 500 g

MSDS


Codice catalogo: (SPCMHY104-500MLGL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: HY104-500MLGL
Codice articolo locale: SPCMHY104-500MLGL
Descrizione: Hydrochloric Acid, 37 Percent, NF is an excellent acidifying reagent.
UOM: 1 * 500 mL


Codice catalogo: (BOSSBS-15482R)
Fornitore: Bioss
Codice articolo fornitore: BS-15482R
Codice articolo locale: BOSSBS-15482R
Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-15482R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-15482R-A555
Codice articolo locale: BOSSBS-15482R-A555
Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6634R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-6634R-A350
Codice articolo locale: BOSSBS-6634R-A350
Descrizione: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl


Fornitore: Spectrum Chemical
Descrizione: Form: Powder

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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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