Hai cercato: NBD+C6-Sphingomyelin

Codice catalogo: (BOSSBS-1635R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-A488

Codice articolo locale: BOSSBS-1635R-A488

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-A680

Codice articolo locale: BOSSBS-1635R-A680

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Fornitore: Apollo Scientific

Descrizione: 4-Chloro-7-nitrobenzofurazan 98%

Fornitore: Thermo Fisher Scientific

Descrizione: 4-Chloro-7-nitrobenzofurazan 98%

MSDS Certificati

Codice catalogo: (ABCAAB272570-100)

Fornitore: Abcam

Codice articolo fornitore: AB272570-100

Codice articolo locale: ABCAAB272570-100

Descrizione: Anti-Sphingomyelin Synthase 2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: 4-Fluoro-7-nitrobenzofurazan 98%

MSDS

Fornitore: Thermo Fisher Scientific

Descrizione: 4-Chloro-7-nitrobenzofurazan ≥99%

MSDS Certificati

Codice catalogo: (BOSSBS-4277R)

Fornitore: Bioss

Codice articolo fornitore: BS-4277R

Codice articolo locale: BOSSBS-4277R

Descrizione: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (APOSBISN0156-10MG)

Fornitore: Apollo Scientific

Codice articolo fornitore: BISN0156-10MG

Codice articolo locale: APOSBISN0156-10MG

Descrizione: GW4869 2HCl is a cell permeable, selective and non-competitve inhibitor of N-SMase (neutral sphingomyelinase), which is important in the metabolism of sphingomyelin producing ceramide and phosphocholine and in cell signaling and regulation.

UOM: 1 * 10 mg

Promo

Codice catalogo: (TCIAA5592-1G)

Fornitore: TCI

Codice articolo fornitore: A5592-1G

Codice articolo locale: TCIAA5592-1G

Descrizione: 4-Chloro-7-nitrobenzofurazan ≥98.0% (by titrimetric analysis) for HPLC labeling

UOM: 1 * 1 g

Promo

Codice catalogo: (90046.)

Fornitore: Biotium

Codice articolo fornitore: 90046

Codice articolo locale: BTIU90046

Descrizione: 4-Fluoro-7-nitrobenzofurazan

UOM: 1 * 25 mg

Promo

Fornitore: Apollo Scientific

Descrizione: For HPLC labeling.

Fornitore: Apollo Scientific

Descrizione: 2-NBDG 95% min

Codice catalogo: (BOSSBS-4216R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-4216R-FITC

Codice articolo locale: BOSSBS-4216R-FITC

Descrizione: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4216R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-4216R-CY3

Codice articolo locale: BOSSBS-4216R-CY3

Descrizione: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4216R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-4216R-A555

Codice articolo locale: BOSSBS-4216R-A555

Descrizione: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

Promo