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Anti-CD63 Mouse Monoclonal Antibody (CF770) [clone: NKI-C3]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BOSSBS-7657R

Anti-BAG6 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-7657R)
Fornitore: Bioss
Codice articolo fornitore: BS-7657R
Codice articolo locale: BOSSBS-7657R
Descrizione: Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin. Acts in part by regulating stability of proteins and their degradation by the proteasome. Participates in endoplasmic reticulum stress-induced apoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation. Also required during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibiting polyubiquitination and subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role in immuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigen presentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins and transfers them to ASNA1/TRC40 for targeting to the endoplasmic reticulum membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11067R-A350

Anti-TECTB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-11067R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-11067R-A350
Codice articolo locale: BOSSBS-11067R-A350
Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11067R-FITC

Anti-TECTB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-11067R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11067R-FITC
Codice articolo locale: BOSSBS-11067R-FITC
Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R

Anti-DLG5 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-13632R)
Fornitore: Bioss
Codice articolo fornitore: BS-13632R
Codice articolo locale: BOSSBS-13632R
Descrizione: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R-CY3

Anti-DLG5 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-13632R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13632R-CY3
Codice articolo locale: BOSSBS-13632R-CY3
Descrizione: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9665R-A647

Anti-MREG Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-9665R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-9665R-A647
Codice articolo locale: BOSSBS-9665R-A647
Descrizione: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity).
UOM: 1 * 100 µl
Product Image-N552-500ML

VWR® Gentle ReView™, Stripping Buffer

Fornitore: VWR Chemicals
Descrizione: Gentle ReView™ Stripping Buffer is a mild, yet effective method for stripping primary and secondary antibodies from PVDF or nitrocellulose membranes.

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Anti-Melanoregulin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-9665R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-9665R-A750
Codice articolo locale: BOSSBS-9665R-A750
Descrizione: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9665R-A680

Anti-Melanoregulin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-9665R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-9665R-A680
Codice articolo locale: BOSSBS-9665R-A680
Descrizione: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity).
UOM: 1 * 100 µl
Image Unavailable-APOSBIP0140-250MG

L-α-Phosphatidylinositol from Glycine max (soybean)

Fornitore: Apollo Scientific
Descrizione: Phospholipid membrane component, precursor of inositol phosphates

Image Unavailable-BOSSBS-1824R-FITC

Anti-HMP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-1824R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-FITC
Codice articolo locale: BOSSBS-1824R-FITC
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1824R-A488

Anti-HMP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-1824R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-A488
Codice articolo locale: BOSSBS-1824R-A488
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2379R-A555

Anti-LAMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-2379R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-2379R-A555
Codice articolo locale: BOSSBS-2379R-A555
Descrizione: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5198R-A555

Anti-ATG16L1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-5198R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-5198R-A555
Codice articolo locale: BOSSBS-5198R-A555
Descrizione: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5198R-A488

Anti-ATG16L1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-5198R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-5198R-A488
Codice articolo locale: BOSSBS-5198R-A488
Descrizione: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
UOM: 1 * 100 µl
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