Hai cercato: DAF-FM+diacetate

Codice catalogo: (BOSSBS-2537R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-2537R-FITC

Codice articolo locale: BOSSBS-2537R-FITC

Descrizione: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2537R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-2537R-A350

Codice articolo locale: BOSSBS-2537R-A350

Descrizione: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

UOM: 1 * 100 µl

Promo

Codice catalogo: (ABNOPAB17198)

Fornitore: Abnova

Codice articolo fornitore: PAB17198

Codice articolo locale: ABNOPAB17198

Descrizione: Rabbit polyclonal antibody raised against synthetic peptide of Daf-2.

UOM: 1 * 100 µG

Promo

Fornitore: Apollo Scientific

Descrizione: 5(6)-Carboxyfluorescein diacetate NHS ester [CFSE (5(6)-CFDA SE)]

Codice catalogo: (ENZOBMLFR1130250)

Fornitore: ENZO LIFE SCIENCES

Codice articolo fornitore: BMLFR1130250

Codice articolo locale: ENZOBMLFR1130250

Descrizione: Potent iron chelator

UOM: 1 * 250 mg

New Product Promo

Codice catalogo: (TCIAE0288-1G)

Fornitore: TCI

Codice articolo fornitore: E0288-1G

Codice articolo locale: TCIAE0288-1G

Descrizione: Ethylenediamine-N,N'-diacetic-N,N'-dipropionic acid hydrate 98,0 Titrimetric

UOM: 1 * 1 g

Promo

Codice catalogo: (BOSSBS-2766R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-2766R-A750

Codice articolo locale: BOSSBS-2766R-A750

Descrizione: FOXO1 is a transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and STK4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BWRLBS3245)

Fornitore: Bioworld Technology

Codice articolo fornitore: BS3245

Codice articolo locale: BWRLBS3245

Descrizione: Synthetic peptide, corresponding to amino acids 691-740 of Human c-Fms.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BWRLBS1532)

Fornitore: Bioworld Technology

Codice articolo fornitore: BS1532

Codice articolo locale: BWRLBS1532

Descrizione: Synthetic peptide, corresponding to amino acids 771-820 of Human c-Fms.

UOM: 1 * 100 µG

Promo

Fornitore: Merck

Descrizione: Manganese (II) acetato tetraidrato zS, Sigma-Aldrich®

MSDS

Fornitore: Merck

Descrizione: Toluene, LiChrosolv® per HPLC, Supelco®

MSDS Promo

Codice catalogo: (MMMAHRXS220A)

Fornitore: 3M

Codice articolo fornitore: HRXS220A

Codice articolo locale: MMMAHRXS220A

Descrizione: The headset helps to protect from potentially harmful workplace noise while at the same time the wearer can listen to the built in AM/FM radio.

UOM: 1 * 1 pezzi

Promo

Codice catalogo: (BOSSBS-2537R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-2537R-CY5.5

Codice articolo locale: BOSSBS-2537R-CY5.5

Descrizione: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2537R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-2537R-A488

Codice articolo locale: BOSSBS-2537R-A488

Descrizione: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.

UOM: 1 * 100 µl

Promo

Codice catalogo: (1.01010.0005)

Fornitore: Merck

Codice articolo fornitore: 1.01010.0005

Codice articolo locale: MERC1.01010.0005

Descrizione: Alizarin complexone dihydrate per la determinazione dei fluoruri, Supelco®

UOM: 1 * 5 g

MSDS Promo

Fornitore: Merck

Descrizione: Toluene, EMPARTA® ACS per analisi, Supelco®

MSDS Promo