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Image Unavailable-BOSSBS-12394R-A350

Anti-DTX2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-12394R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12394R-A350
Codice articolo locale: BOSSBS-12394R-A350
Descrizione: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12394R-FITC

Anti-DTX2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-12394R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-12394R-FITC
Codice articolo locale: BOSSBS-12394R-FITC
Descrizione: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context; mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0399R-A350

Anti-DTX1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-0399R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-0399R-A350
Codice articolo locale: BOSSBS-0399R-A350
Descrizione: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0399R-A488

Anti-DTX1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-0399R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-0399R-A488
Codice articolo locale: BOSSBS-0399R-A488
Descrizione: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0399R-A647

Anti-DTX1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-0399R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-0399R-A647
Codice articolo locale: BOSSBS-0399R-A647
Descrizione: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0380R-CY5

Anti-MBP Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-0380R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-0380R-CY5
Codice articolo locale: BOSSBS-0380R-CY5
Descrizione: Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11238R-A750

Anti-SHANK2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Codice catalogo: (BOSSBS-11238R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11238R-A750
Codice articolo locale: BOSSBS-11238R-A750
Descrizione: SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localisation of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.
UOM: 1 * 100 µl
Image Unavailable-UVPA30-0057-01

Calibration lamps, CP series, Pen-Ray®

Fornitore: UVP ULTRA VIOLET PRODUCTS
Descrizione: Lampada spettro, Pen-Ray®, Lampada di calibrazione, serie CP, 254 nm, 69,6 mm

Product Image-516-0196

Chiusura per tubi da dialisi, Spectra/Por®

Fornitore: Spectrum Laboratories
Descrizione: Chiusure standard
In PP, autoclavabile
Solo per membrane in cellulosa rigenerata
Più leggere dell'acqua, utilizzate normalmente in combinazione con chiusure zavorrate
Scegliere un tappo 4 - 10 mm più grande della larghezza piatta del tubo

Product Image-UVPA90-0069-06

Zinc and cadimum spectrum lamps

Fornitore: UVP ULTRA VIOLET PRODUCTS
Descrizione: Lampada spettro, Zinco, cavi radiali, 203 mm

Image Unavailable-BNC681100-500

Anti-Cytokeratin Mouse Monoclonal Antibody (CF568) [clone: KRTL/1077 KRTH/1076]

Fornitore: Biotium
Descrizione: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Image Unavailable-BNC401100-500

Anti-Cytokeratin Mouse Monoclonal Antibody (CF640R) [clone: KRTL/1077 KRTH/1076]

Fornitore: Biotium
Descrizione: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Image Unavailable-BNUB1100-500

Anti-Cytokeratin Mouse Monoclonal Antibody [clone: KRTL/1077 KRTH/1076]

Fornitore: Biotium
Descrizione: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Image Unavailable-J66306.MC

Mezlocillin sodium salt

Codice catalogo: (J66306.MC)
Fornitore: Thermo Fisher Scientific
Codice articolo fornitore: J66306.MC
Codice articolo locale: ALFAJ66306.MC
Descrizione: A broad spectrum antibiotic.
UOM: 1 * 100 mg

Certificati


Image Unavailable-J66206.MC

Cefotetan disodium

Codice catalogo: (J66206.MC)
Fornitore: Thermo Fisher Scientific
Codice articolo fornitore: J66206.MC
Codice articolo locale: ALFAJ66206.MC
Descrizione: A broad spectrum antibiotic.
UOM: 1 * 100 mg

Certificati


Image Unavailable-BOSSBS-11238R-A647

Anti-SHANK2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-11238R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11238R-A647
Codice articolo locale: BOSSBS-11238R-A647
Descrizione: SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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