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Fornitore: Spectrum Chemical
Descrizione: Monosodium L-Glutamate, FCC is used in the food industry as a flavor with an umami taste. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Codice catalogo: (BOSSBS-1546R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1546R-HRP
Codice articolo locale: BOSSBS-1546R-HRP
Descrizione: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7144R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-7144R-A350
Codice articolo locale: BOSSBS-7144R-A350
Descrizione: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2966R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-2966R-A647
Codice articolo locale: BOSSBS-2966R-A647
Descrizione: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2966R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-2966R-CY5
Codice articolo locale: BOSSBS-2966R-CY5
Descrizione: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6335R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-6335R-A750
Codice articolo locale: BOSSBS-6335R-A750
Descrizione: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
UOM: 1 * 100 µl


Codice catalogo: (SPECACR1-U2S-01N)
Fornitore: Spectrum Laboratories
Codice articolo fornitore: ACR1-U2S-01N
Codice articolo locale: SPECACR1-U2S-01N
Descrizione: Spectrum's KrosFlo Research I (KRI) system combines a digital peristaltic pump and a multi-purpose lab stand to provide ultimate convenience and efficiency for experiments involving fluid circulation and transfers. The easy-to-operate digital KRI pump drives the fluid stream through flexible tubing (to be order separately) while the incorporated stand and included holders secure the tubing, filters, reservoirs and other components in place.
UOM: 1 * 1 pezzi


Fornitore: Spectrum Laboratories
Descrizione: Hollow fibre filter modules are particularly useful in tangential flow filtration because processes can easily be scaled-up from small volume applications to full-scale production.

Codice catalogo: (BOSSBS-11955R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11955R-CY3
Codice articolo locale: BOSSBS-11955R-CY3
Descrizione: SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (EDQMY0000215)
Fornitore: EDQM
Codice articolo fornitore: Y0000215
Codice articolo locale: EDQMY0000215
Descrizione: Organic Standard, Pravastatin sodium - reference spectrum
UOM: 1 * 1 pezzi


Fornitore: AAT BIOQUEST
Descrizione: This fluorescein-12-dUTP conjugate can be used as a green fluorescence color with Spectrum Green™ filter set (Spectrum Green™ is the trademark of Vysis).

New Product

Codice catalogo: (BOSSBS-11238R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11238R-A750
Codice articolo locale: BOSSBS-11238R-A750
Descrizione: SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localisation of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.
UOM: 1 * 100 µl


Codice catalogo: (ZEIS3901580000000)
Fornitore: ZEISS
Codice articolo fornitore: 3901580000000
Codice articolo locale: ZEIS3901580000000
Descrizione: Lampada spettro, Tungsten lamp filament, 6 V, 30 W
UOM: 1 * 1 pezzi


Codice catalogo: (BOSSBS-11238R)
Fornitore: Bioss
Codice articolo fornitore: BS-11238R
Codice articolo locale: BOSSBS-11238R
Descrizione: SH3 and multiple ankyrin repeat domains 1-3 (Shank1-3) of the Shank/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). The PSD is an electron-dense structure underneath the postsynaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the presynaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). Shank recruits betaPIX and PAK to spines to regulate postsynaptic structure and interacts with NMDA receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6273R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-6273R-A647
Codice articolo locale: BOSSBS-6273R-A647
Descrizione: Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0399R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-0399R-CY3
Codice articolo locale: BOSSBS-0399R-CY3
Descrizione: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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