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Image Unavailable-BOSSBS-7048R-FITC

Anti-INPPL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-7048R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7048R-FITC
Codice articolo locale: BOSSBS-7048R-FITC
Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7048R-CY3

Anti-INPPL1 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-7048R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-7048R-CY3
Codice articolo locale: BOSSBS-7048R-CY3
Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7048R-A350

Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-7048R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-7048R-A350
Codice articolo locale: BOSSBS-7048R-A350
Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM: 1 * 100 µl
Product Image-461-1428

Immersion thermostats, MAGIO™ MS and MX

Fornitore: Julabo GmbH
Descrizione: The MAGIO™ series of bridge mounted circulators operate with a working temperature range of −50 to +300 °C* and a heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ immersion thermostats can be adapted to different tanks and applications.

Image Unavailable-PRCI1400-16-PDC

Lab Markers, several colours

Fornitore: PRECISION DYNAMICS
Descrizione: Versatile, permanent markings write on plastic, metal, and porcelain labware.

Product Image-611-2581

Bilance industriali, bilancia da banco compatta Ranger® 3000

Fornitore: OHAUS
Descrizione: Bilancia multiuso compatta e semplice da utilizzare per risultati rapidi e precisi. Le modalità di applicazione includono: pesata, pesata percentuale, conteggio pezzi, accumulazione e pesatura dinamica.

Product Image-611-3408

Bilance da banco industriali, Ranger serie 4000

Fornitore: OHAUS
Descrizione: Bilancia multiuso compatta per la produzione rapida di risultati precisi. Modalità di applicazione: pesata, pesata percentuale, conteggio dei pezzi, accumulazione e pesatura dinamica e funzione hold del display

Image Unavailable-PRTWDX474MBRL

DX4™ Softshell Jackets

Fornitore: Portwest
Descrizione: The DX4 Softshell jacket is precision engineered using a revolutionary breathable, waterproof, and windproof ripstop fabric. Its sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims, and multiple secure pockets for ample storage. An ideal choice for the modern worker.

Product Image-PRTWDX474BKRS

Softshell jackets, DX4™, DX474

Fornitore: Portwest
Descrizione: The DX4™ Softshell Jackets are precision engineered using a revolutionary breathable, waterproof and windproof ripstop fabric. These sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims and multiple secure pockets for ample storage. An ideal choice for the modern worker.

Product Image-471-1051

Frigoriferi da laboratorio, Compact, Mediline

Fornitore: Liebherr
Descrizione: Questi frigoriferi da laboratorio MediLine dotati di funzione comfort controller, forniscono il massimo spazio di conservazione su un ingombro di 60 cm di larghezza. I modelli sottobanco sono alti 820 mm e entrano sotto quasi tutti i banchi da laboratorio. Questi apparecchi soddisfano le rigide esigenze di refrigerazione di laboratorio.

Product Image-611-3224

Bilance di precisione, Adventurer®

Fornitore: OHAUS
Descrizione: Una gamma di bilance con numerose funzionalità e semplici da utilizzare, per risultati di pesata rapidi e accurati nelle attività di pesatura e misurazione di routine. Le applicazioni comprendono pesata, formulazione, pesata dinamica, conteggio delle parti, totalizzazione, determinazione della densità, controllo della pesata e pesata in percentuale. I tipici tempi di stabilizzazione sono meno di 2 secondi.

Product Image-RPN2232

Western blotting detection reagent, Amersham™ ECL™ Prime

Fornitore: Cytiva
Descrizione: Amersham™ ECL™ Prime is a highly sensitive Western blotting detection reagent characterised by stable signal emission, allowing for the possibility of repeated exposures and making it easier to process several blots in the same experimental run. Amersham™ ECL™ Prime delivers a detection system that is sensitive, stable, precisely quantitative across a wide dynamic range of protein levels, and conservative in its consumption of expensive antibody reagents. The high performance of Amersham™ ECL™ Prime is due to the presence of an enhancer in the reagent, increasing enzyme turnover, and thereby significantly increasing both signal intensity and duration. The light signal is further intensified by the addition of a catalyst.

Product Image-461-1423

Termostati, Serie MAGIO™ MS e MX

Fornitore: Julabo GmbH
Descrizione: MAGIO™ funziona con un range di temperatura da 20 a +300 °C e potenza termica fino a 3 kW. Con la loro potente pompa di pressione/aspirazione, le unità MAGIO™ sono ideali per applicazioni di controllo esterno della temperatura. Un'ampia gamma di accessori e un'eccellente dinamica fanno sì che i circolatori MAGIO™ possano essere adattati modularmente e specifico per le diverse applicazioni.

Product Image-LAUDL002683

Heating and cooling process thermostats, Integral XT

Fornitore: LAUDA
Descrizione: Process thermostats with integrated cooling system for dynamic temperature control within external circuits.

New Product

Product Image-462-0639

Circolatori refrigerati e riscaldanti, MAGIO™ serie MS

Fornitore: Julabo GmbH
Descrizione: La serie MAGIO™ di circolatori refrigeranti e riscaldanti funzionano con una gamma di temperatura operativa che va da –50 a +300 °C e con una capacità riscaldante fino a 3 kW. Con la loro potente pompa di pressione/aspirazione, le unità MAGIO™ sono ideali per applicazioni a temperatura esterna. Una vasta gamma di accessori e un'eccellente dinamica fanno sì che i circolatori MAGIO™ possano essere adattati in modo modulare e individuale alle applicazioni.

Environmentally Preferable

Product Image-LAUDL002666

Heating and cooling process thermostats, Integral T

Fornitore: LAUDA
Descrizione: Integral T are process thermostats with an integrated cooling system for dynamic temperature control within external circuits.

Prezzo a richiesta
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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