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Fornitore: Merck
Descrizione: Syringe filters with hydrophobic PVDF membrane. Used in vacuum line protection, transducer protection and gas filtration. Available as either 25 mm or pump-driven Millex®-FG₅₀ 50 mm diameter filters.

Fornitore: Sartorius
Descrizione: Setto poroso in acciaio inox per filtri a membrana Ø 50 mm

Codice catalogo: (BOSSBS-11511R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11511R-CY3
Codice articolo locale: BOSSBS-11511R-CY3
Descrizione: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13356R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-13356R-HRP
Codice articolo locale: BOSSBS-13356R-HRP
Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13356R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13356R-A488
Codice articolo locale: BOSSBS-13356R-A488
Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13356R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13356R-CY5
Codice articolo locale: BOSSBS-13356R-CY5
Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
UOM: 1 * 100 µl


Fornitore: Cytiva (Formerly Pall Lab)
Descrizione: ValuPrep syringe filters offer the confidence of Pall membranes in economic 1000 packs.

Codice catalogo: (BOSSBS-13695R)
Fornitore: Bioss
Codice articolo fornitore: BS-13695R
Codice articolo locale: BOSSBS-13695R
Descrizione: The Src family of protein tyrosine kinases (Src-PTKs) is important in the regulation of growth and differentiation of eukaryotic cells. The activity of Src-PTKs in cells of different types is negatively controlled by Csk. Csk binding protein (Cbp), also designated phosphoprotein associated with glycosphingo-lipid-enriched microdomains (GEMs) or PAG, is a ubiquitously expressed transmembrane phosphoprotein that binds specifically to the SH2 domain of Csk. Cbp is involved in the membrane localization of Csk and in Csk-mediated inhibition of c-Src. In the plasma membrane, Cbp is exclusively localized in the GM1 ganglioside-enriched detergent-insoluble membrane domain, which is important in receptor-mediated signaling. Cbp is a component of the regulatory mechanism controlling the activity of membrane-associated Src-PTKs.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11507R)
Fornitore: Bioss
Codice articolo fornitore: BS-11507R
Codice articolo locale: BOSSBS-11507R
Descrizione: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2673R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-2673R-CY5.5
Codice articolo locale: BOSSBS-2673R-CY5.5
Descrizione: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11067R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11067R-A750
Codice articolo locale: BOSSBS-11067R-A750
Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesised as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialised sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13695R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13695R-CY3
Codice articolo locale: BOSSBS-13695R-CY3
Descrizione: The Src family of protein tyrosine kinases (Src-PTKs) is important in the regulation of growth and differentiation of eukaryotic cells. The activity of Src-PTKs in cells of different types is negatively controlled by Csk. Csk binding protein (Cbp), also designated phosphoprotein associated with glycosphingo-lipid-enriched microdomains (GEMs) or PAG, is a ubiquitously expressed transmembrane phosphoprotein that binds specifically to the SH2 domain of Csk. Cbp is involved in the membrane localization of Csk and in Csk-mediated inhibition of c-Src. In the plasma membrane, Cbp is exclusively localized in the GM1 ganglioside-enriched detergent-insoluble membrane domain, which is important in receptor-mediated signaling. Cbp is a component of the regulatory mechanism controlling the activity of membrane-associated Src-PTKs.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9744R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-9744R-CY5.5
Codice articolo locale: BOSSBS-9744R-CY5.5
Descrizione: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9744R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-9744R-A647
Codice articolo locale: BOSSBS-9744R-A647
Descrizione: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1343R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1343R-HRP
Codice articolo locale: BOSSBS-1343R-HRP
Descrizione: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2673R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-2673R-HRP
Codice articolo locale: BOSSBS-2673R-HRP
Descrizione: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
UOM: 1 * 100 µl


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