Hai cercato: Membrane+filtranti

Codice catalogo: (BOSSBS-7097R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-7097R-A350

Codice articolo locale: BOSSBS-7097R-A350

Descrizione: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6168R)

Fornitore: Bioss

Codice articolo fornitore: BS-6168R

Codice articolo locale: BOSSBS-6168R

Descrizione: RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13708R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-13708R-CY3

Codice articolo locale: BOSSBS-13708R-CY3

Descrizione: Anchoring filament protein which is a component of the basement membrane zone.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1343R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-1343R-CY7

Codice articolo locale: BOSSBS-1343R-CY7

Descrizione: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5081R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-5081R-A680

Codice articolo locale: BOSSBS-5081R-A680

Descrizione: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organisation. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5081R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-5081R-A750

Codice articolo locale: BOSSBS-5081R-A750

Descrizione: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organisation. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5081R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-5081R-A350

Codice articolo locale: BOSSBS-5081R-A350

Descrizione: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

UOM: 1 * 100 µl

Promo

Fornitore: Abcam

Descrizione: Rabbit monoclonal [EPR13414] to Zonula occludens protein 3/ZO3 - Plasma Membrane Marker.

New Product

Codice catalogo: (BOSSBS-1558R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-1558R-A555

Codice articolo locale: BOSSBS-1558R-A555

Descrizione: Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3667R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-3667R-CY3

Codice articolo locale: BOSSBS-3667R-CY3

Descrizione: Choline transporter. May be involved in membrane synthesis and myelin production.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2945R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-2945R-A750

Codice articolo locale: BOSSBS-2945R-A750

Descrizione: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2945R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-2945R-CY7

Codice articolo locale: BOSSBS-2945R-CY7

Descrizione: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BNUM0097-50)

Fornitore: Biotium

Codice articolo fornitore: BNUM0097-50

Codice articolo locale: BTIUBNUM0097-50

Descrizione: This antibody recognizes an antigen associated with the nuclear membrane expressed in human cells. It can be used to stain the nuclear membrane in cell or tissue preparations and can be used as a marker of the nuclear membrane in subcellular fractions. It produces a ring pattern around the nucleus of cells of normal and malignant cells and may be used to stain the nuclear membrane of cells in fixed or frozen tissue sections. ,The nuclear envelope (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is the double membrane of the nucleus that encloses genetic material in eukaryotic cells. It separates the contents of the nucleus (DNA in particular) from the cytosol (cytoplasm). Numerous nuclear pores are present on the nuclear envelope to facilitate and regulate the exchange of materials (for example, proteins and RNA) between the nucleus and the cytoplasm. The space between the two membranes that make up the nuclear envelope is called the perinuclear space (also called the perinuclear cisterna), and is usually about 20 - 40 nm wide. Each of the two membranes is composed of a lipid bilayer. The outer membrane is continuous with the rough endoplasmic reticulum. The inner membrane is erected upon the nuclear lamina, a network of intermediate filaments made of lamin, that plays a role in mitosis and meiosis. The type of lamins present are A, B1, B2, and C. The nuclear envelope may also play a role in the disposition of chromatin inside the nucleus. The lamina acts as a site of attachment for chromosomes. It also acts like a shield for the nucleus. During prophase in mitosis, the chromatids begin condensing to form chromosomes, and the nuclear envelope begins to disintegrate. During metaphase, the nuclear envelope is completely disintegrated, and the chromosomes can be pulled apart as chromatids by the spindle fibers.

UOM: 1 * 50 µl

Promo

Codice catalogo: (BOSSBS-11067R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-11067R-A647

Codice articolo locale: BOSSBS-11067R-A647

Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11360R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-11360R-FITC

Codice articolo locale: BOSSBS-11360R-FITC

Descrizione: Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis.Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1112R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-1112R-CY3

Codice articolo locale: BOSSBS-1112R-CY3

Descrizione: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome. (Also known as glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7; Glypican-3 precursor).

UOM: 1 * 100 µl

Promo