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Image Unavailable-BOSSBS-1824R-FITC

Anti-HMP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-1824R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-FITC
Codice articolo locale: BOSSBS-1824R-FITC
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1824R-A488

Anti-HMP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-1824R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-A488
Codice articolo locale: BOSSBS-1824R-A488
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13110R-A647

Anti-ETFDH Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-13110R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13110R-A647
Codice articolo locale: BOSSBS-13110R-A647
Descrizione: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13110R-FITC

Anti-ETFDH Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-13110R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13110R-FITC
Codice articolo locale: BOSSBS-13110R-FITC
Descrizione: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1824R-A680

Anti-Mitofilin/IMMT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-1824R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-1824R-A680
Codice articolo locale: BOSSBS-1824R-A680
Descrizione: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2945R-FITC

Anti-SNX1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-2945R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-2945R-FITC
Codice articolo locale: BOSSBS-2945R-FITC
Descrizione: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2945R-HRP

Anti-SNX1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-2945R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-2945R-HRP
Codice articolo locale: BOSSBS-2945R-HRP
Descrizione: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1112R-A750

Anti-Glypican 3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-1112R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-1112R-A750
Codice articolo locale: BOSSBS-1112R-A750
Descrizione: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome. (Also known as glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7; Glypican-3 precursor).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R-CY3

Anti-DLG5 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-13632R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13632R-CY3
Codice articolo locale: BOSSBS-13632R-CY3
Descrizione: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R

Anti-DLG5 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-13632R)
Fornitore: Bioss
Codice articolo fornitore: BS-13632R
Codice articolo locale: BOSSBS-13632R
Descrizione: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
Image Unavailable-30585-1G

Bis(1-butylpentyl)decane-1,10-diyl diglutarate ≥97%, Selectophore™ ionophore, Supelco®

Codice catalogo: (30585-1G)
Fornitore: Merck
Codice articolo fornitore: 30585-1G
Codice articolo locale: SUPL30585-1G
Descrizione: Bis(1-butylpentyl)decane-1,10-diyl diglutarate, was used for the preparation of optode membranes, which are sodium selective and are based on neutral ionophore, primarily used for the characterization of total sodium concentration in human blood plasma.
UOM: 1 * 1 g
Product Image-PALLMSTGXT25S16

Syringe filters for ion exchange chromatography, XT Acrodisc®

Fornitore: Cytiva (Formerly Pall Lab)
Descrizione: These XT Acrodisc® units with Mustang® Q membrane are designed for laboratory use and scale-down process development.

Image Unavailable-BOSSBS-6916R-A680

Anti-RABX5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-6916R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6916R-A680
Codice articolo locale: BOSSBS-6916R-A680
Descrizione: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2675R-A647

Anti-PTPRJ Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-2675R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-2675R-A647
Codice articolo locale: BOSSBS-2675R-A647
Descrizione: a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9712R-CY7

Anti-SLC9B2 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-9712R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-CY7
Codice articolo locale: BOSSBS-9712R-CY7
Descrizione: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9712R-A680

Anti-NHEDC2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-9712R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-A680
Codice articolo locale: BOSSBS-9712R-A680
Descrizione: Na⁺/H⁺ exchangers (NHEs) catalyse the transport of Na⁺ in exchange for H⁺ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na⁺/H⁺ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na⁺ and Li⁺ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl
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