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Image Unavailable-SPCMZ1088-25KGBL

Zinc picolinate, in polvere 200-400 Mesh

Codice catalogo: (SPCMZ1088-25KGBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: Z1088-25KGBL
Codice articolo locale: SPCMZ1088-25KGBL
Descrizione: Zinc Picolinate, 200 to 400 Mesh, Powder is most commonly used as a nutritional food supplement as a source for zinc and aspartic acid.
UOM: 1 * 25 kg
Image Unavailable-BOSSBS-15482R-A750

Anti-hHR23b Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Codice catalogo: (BOSSBS-15482R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-15482R-A750
Codice articolo locale: BOSSBS-15482R-A750
Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15482R-CY5

Anti-hHR23b Rabbit Polyclonal Antibody (Cy5)

Codice catalogo: (BOSSBS-15482R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-15482R-CY5
Codice articolo locale: BOSSBS-15482R-CY5
Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A750

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-6634R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-6634R-A750
Codice articolo locale: BOSSBS-6634R-A750
Descrizione: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-SPCMCA184-100GM

Carbomer 934P resin, in polvere NF

Codice catalogo: (SPCMCA184-100GM)
Fornitore: Spectrum Chemical
Codice articolo fornitore: CA184-100GM
Codice articolo locale: SPCMCA184-100GM
Descrizione: Carbomer 934P, Resin, NF polymers can provide bioadhesion and good binding characteristics that provide highly effective controlled-release properties.
UOM: 1 * 100 g
Image Unavailable-SPCMB2411-200LTBL

Benzyl acetate ≥98%

Codice catalogo: (SPCMB2411-200LTBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: B2411-200LTBL
Codice articolo locale: SPCMB2411-200LTBL
Descrizione: Benzyl Acetate, an organic compound, is the ester formed by condensation of acetic acid and benzyl alcohol; it is the main constituent of the essential oils from jasmine flowers.
UOM: 1 * 200 L
Image Unavailable-SPCMCA150-12KG

Calcio idrossido, in polvere USP, Ph. Eur., BP, JP

Fornitore: Spectrum Chemical
Descrizione: Kosher certified

MSDS

Image Unavailable-SPCMAL228-2.5KGBL

Aluminum monostearate NF

Fornitore: Spectrum Chemical
Descrizione: Aluminum Monostearate, NF is also known as Dihydroxyaluminum stearate.

Image Unavailable-SPCME1172-100GM

Etile oleato NF

Fornitore: Spectrum Chemical
Descrizione: Ethyl Oleate, NF is used as a solubilizing agent in pharmaceutical preparations. 

Image Unavailable-SPCMZI115-2.5KG

Zinc stearate, in polvere USP

Fornitore: Spectrum Chemical
Descrizione: Zinc stearate, in polvere USP

Certificati

Image Unavailable-SPCMD3009-10KGBL

Dodecyltrimethylammonium bromide

Codice catalogo: (SPCMD3009-10KGBL)
Fornitore: Spectrum Chemical
Codice articolo fornitore: D3009-10KGBL
Codice articolo locale: SPCMD3009-10KGBL
Descrizione: Dodecyltrimethylammonium Bromide is a quaternary ammonium salt useful as paint strippers, foaming stabilizers, and bactericidal lotions.
UOM: 1 * 10 kg
Image Unavailable-SPCMH1136-2.5KG

Hydroxypropyl methylcellulose (Hypromellose), 100,000 mPa.s USP Substitution Type 2208

Codice catalogo: (SPCMH1136-2.5KG)
Fornitore: Spectrum Chemical
Codice articolo fornitore: H1136-2.5KG
Codice articolo locale: SPCMH1136-2.5KG
Descrizione: Hypromellose, Substitution Type 2208, 100,000 mPa.s, USP.
UOM: 1 * 2,5 kg
Image Unavailable-BOSSBS-15482R-FITC

Anti-hHR23b Rabbit Polyclonal Antibody (FITC)

Codice catalogo: (BOSSBS-15482R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-15482R-FITC
Codice articolo locale: BOSSBS-15482R-FITC
Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM: 1 * 100 µl
Image Unavailable-SPCMA1253-1KG

L-Alanina USP

Fornitore: Spectrum Chemical
Descrizione: L-Alanina USP

Image Unavailable-SPCMCR105-1KGBL

Creatine (N-amidinosarcosine) monohydrate

Fornitore: Spectrum Chemical
Descrizione: Creatine (N-amidinosarcosine) monohydrate

Image Unavailable-SPCMP1582-5KGBL

L-Fenilalanina USP

Fornitore: Spectrum Chemical
Descrizione: L-Fenilalanina USP

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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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