Hai cercato: genomes

Codice catalogo: (BOSSBS-8586R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-8586R-CY5.5

Codice articolo locale: BOSSBS-8586R-CY5.5

Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-A350

Codice articolo locale: BOSSBS-2747R-A350

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-CY3

Codice articolo locale: BOSSBS-2747R-CY3

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-CY5

Codice articolo locale: BOSSBS-2747R-CY5

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-CY7

Codice articolo locale: BOSSBS-3067R-CY7

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-A350

Codice articolo locale: BOSSBS-3067R-A350

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6369R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6369R-FITC

Codice articolo locale: BOSSBS-6369R-FITC

Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI33-612)

Fornitore: ProSci Inc.

Codice articolo fornitore: 33-612

Codice articolo locale: PRSI33-612

Descrizione: BRCA1 (Breast cancer type 1 susceptibility protein) is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-8444R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-8444R-A750

Codice articolo locale: BOSSBS-8444R-A750

Descrizione: This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localisation and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI56-268)

Fornitore: ProSci Inc.

Codice articolo fornitore: 56-268

Codice articolo locale: PRSI56-268

Descrizione: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.

UOM: 1 * 400 µl

Promo

Codice catalogo: (BOSSBS-6369R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-6369R-CY7

Codice articolo locale: BOSSBS-6369R-CY7

Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-CY3

Codice articolo locale: BOSSBS-3067R-CY3

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-CY5.5

Codice articolo locale: BOSSBS-3067R-CY5.5

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-CY5

Codice articolo locale: BOSSBS-3067R-CY5

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-A555

Codice articolo locale: BOSSBS-3067R-A555

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8586R)

Fornitore: Bioss

Codice articolo fornitore: BS-8586R

Codice articolo locale: BOSSBS-8586R

Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

UOM: 1 * 100 µl

Promo