Hai cercato: genomes

Codice catalogo: (BOSSBS-8586R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-8586R-CY3

Codice articolo locale: BOSSBS-8586R-CY3

Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12278R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-12278R-CY7

Codice articolo locale: BOSSBS-12278R-CY7

Descrizione: SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-CY7

Codice articolo locale: BOSSBS-3067R-CY7

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3067R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-3067R-A350

Codice articolo locale: BOSSBS-3067R-A350

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R

Codice articolo locale: BOSSBS-2747R

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6107R)

Fornitore: Bioss

Codice articolo fornitore: BS-6107R

Codice articolo locale: BOSSBS-6107R

Descrizione: Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8586R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-8586R-CY5.5

Codice articolo locale: BOSSBS-8586R-CY5.5

Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-CY3

Codice articolo locale: BOSSBS-2747R-CY3

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-CY5

Codice articolo locale: BOSSBS-2747R-CY5

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2747R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-A350

Codice articolo locale: BOSSBS-2747R-A350

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6369R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6369R-FITC

Codice articolo locale: BOSSBS-6369R-FITC

Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI28-429)

Fornitore: ProSci Inc.

Codice articolo fornitore: 28-429

Codice articolo locale: PRSI28-429

Descrizione: The HSFY1 gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. HSFY1 is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI33-612)

Fornitore: ProSci Inc.

Codice articolo fornitore: 33-612

Codice articolo locale: PRSI33-612

Descrizione: BRCA1 (Breast cancer type 1 susceptibility protein) is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-2747R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-2747R-FITC

Codice articolo locale: BOSSBS-2747R-FITC

Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6369R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-6369R-CY3

Codice articolo locale: BOSSBS-6369R-CY3

Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8586R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-8586R-A555

Codice articolo locale: BOSSBS-8586R-A555

Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

UOM: 1 * 100 µl

Promo