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Codice catalogo: (BOSSBS-3067R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-3067R-HRP
Codice articolo locale: BOSSBS-3067R-HRP
Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6369R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-6369R-CY5
Codice articolo locale: BOSSBS-6369R-CY5
Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6369R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-6369R-A488
Codice articolo locale: BOSSBS-6369R-A488
Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3067R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-3067R-A647
Codice articolo locale: BOSSBS-3067R-A647
Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6369R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-6369R-A350
Codice articolo locale: BOSSBS-6369R-A350
Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2370R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-2370R-CY3
Codice articolo locale: BOSSBS-2370R-CY3
Descrizione: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6369R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-6369R-A555
Codice articolo locale: BOSSBS-6369R-A555
Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6369R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6369R-CY5.5
Codice articolo locale: BOSSBS-6369R-CY5.5
Descrizione: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2747R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-2747R-A555
Codice articolo locale: BOSSBS-2747R-A555
Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2370R)
Fornitore: Bioss
Codice articolo fornitore: BS-2370R
Codice articolo locale: BOSSBS-2370R
Descrizione: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3067R)
Fornitore: Bioss
Codice articolo fornitore: BS-3067R
Codice articolo locale: BOSSBS-3067R
Descrizione: The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6107R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-6107R-CY3
Codice articolo locale: BOSSBS-6107R-CY3
Descrizione: Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8586R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-8586R-CY3
Codice articolo locale: BOSSBS-8586R-CY3
Descrizione: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12278R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-12278R-CY7
Codice articolo locale: BOSSBS-12278R-CY7
Descrizione: SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2370R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-2370R-FITC
Codice articolo locale: BOSSBS-2370R-FITC
Descrizione: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12278R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12278R-A350
Codice articolo locale: BOSSBS-12278R-A350
Descrizione: SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
UOM: 1 * 100 µl


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