Hai cercato: N-Carbobenzoxy-L-tyrosine

Codice catalogo: (BOSSBS-12914R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-12914R-HRP

Codice articolo locale: BOSSBS-12914R-HRP

Descrizione: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6914R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-6914R-A680

Codice articolo locale: BOSSBS-6914R-A680

Descrizione: Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.

UOM: 1 * 100 µl

Promo

Codice catalogo: (USBI132072)

Fornitore: US Biological

Codice articolo fornitore: 132072

Codice articolo locale: USBI132072

Descrizione: Anti-PTPN7 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-11066R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-11066R-A488

Codice articolo locale: BOSSBS-11066R-A488

Descrizione: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11066R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-11066R-HRP

Codice articolo locale: BOSSBS-11066R-HRP

Descrizione: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11066R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-11066R-CY7

Codice articolo locale: BOSSBS-11066R-CY7

Descrizione: The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6914R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-6914R-CY5

Codice articolo locale: BOSSBS-6914R-CY5

Descrizione: Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13667R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-13667R-CY3

Codice articolo locale: BOSSBS-13667R-CY3

Descrizione: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3182R)

Fornitore: Bioss

Codice articolo fornitore: BS-3182R

Codice articolo locale: BOSSBS-3182R

Descrizione: Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs), growth factors and cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin receptor, cytokine receptors as well as B and T cell antigen receptors; Gab2 acts as a docking protein for several SH2-containing proteins. Upon tyrosine phosphorylation, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, CrkL and SHC.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13699R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-13699R-A680

Codice articolo locale: BOSSBS-13699R-A680

Descrizione: Sam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC ?. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC ?, Fyn and Ras GAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC ?, Fyn or Ras GAP, indicating that SLM-2 may not be an adapter protein for these proteins.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13667R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-13667R-FITC

Codice articolo locale: BOSSBS-13667R-FITC

Descrizione: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13699R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-13699R-A555

Codice articolo locale: BOSSBS-13699R-A555

Descrizione: Sam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC ?. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC ?, Fyn and Ras GAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC ?, Fyn or Ras GAP, indicating that SLM-2 may not be an adapter protein for these proteins.

UOM: 1 * 100 µl

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride 95%

MSDS

Codice catalogo: (BOSSBS-6235R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6235R-FITC

Codice articolo locale: BOSSBS-6235R-FITC

Descrizione: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6235R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-6235R-A750

Codice articolo locale: BOSSBS-6235R-A750

Descrizione: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15500R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-15500R-A488

Codice articolo locale: BOSSBS-15500R-A488

Descrizione: LTK is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo