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Image Unavailable-BOSSBS-11190R-A680

Anti-C9a/C9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-11190R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11190R-A680
Codice articolo locale: BOSSBS-11190R-A680
Descrizione: C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15307R-FITC

Anti-Complement component C9b Rabbit Polyclonal Antibody (FITC)

Codice catalogo: (BOSSBS-15307R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-15307R-FITC
Codice articolo locale: BOSSBS-15307R-FITC
Descrizione: C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12305R-CY3

Anti-USE1 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-12305R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-12305R-CY3
Codice articolo locale: BOSSBS-12305R-CY3
Descrizione: In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12305R-HRP

Anti-USE1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-12305R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-12305R-HRP
Codice articolo locale: BOSSBS-12305R-HRP
Descrizione: In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12305R

Anti-USE1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-12305R)
Fornitore: Bioss
Codice articolo fornitore: BS-12305R
Codice articolo locale: BOSSBS-12305R
Descrizione: In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6767R

Anti-PDCD6IP Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-6767R)
Fornitore: Bioss
Codice articolo fornitore: BS-6767R
Codice articolo locale: BOSSBS-6767R
Descrizione: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6857R-A680

Anti-beta COP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-6857R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6857R-A680
Codice articolo locale: BOSSBS-6857R-A680
Descrizione: The Golgi complex is a key organelle where processing and sorting of newly synthesised proteins occurs. Membrane traffic from the endoplasmic reticulum (ER) to the Golgi complex and from the Golgi complex to the different final cellular destinations is believed to be mediated by carrier vesicles. Two populations of coated vesicles mediate biosynthetic membrane traffic between the different membrane-bound compartments. Clathrin-coated vesicles carry proteins to endocytic organelles and secretory granules, whilst non-clathrin-coated vesicles are involved in intra-Golgi transport and transport from the ER to the Golgi complex. Beta COP is a member of a set of protein which are believed to associate with the non-clathrin coated vesicles. Golgi-derived non-clathrin-coated vesicles are believed to act as bulk carriers, whereas clathrin-coated vesicles carry a selective cargo of membrane proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11067R-A647

Anti-TECTB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-11067R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11067R-A647
Codice articolo locale: BOSSBS-11067R-A647
Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15466R-A680

Anti-Syncytin 2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Codice catalogo: (BOSSBS-15466R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-15466R-A680
Codice articolo locale: BOSSBS-15466R-A680
Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15466R-CY5

Anti-Syncytin 2 Rabbit Polyclonal Antibody (Cy5)

Codice catalogo: (BOSSBS-15466R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-15466R-CY5
Codice articolo locale: BOSSBS-15466R-CY5
Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15466R-CY7

Anti-Syncytin 2 Rabbit Polyclonal Antibody (Cy7)

Codice catalogo: (BOSSBS-15466R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-15466R-CY7
Codice articolo locale: BOSSBS-15466R-CY7
Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7744R-CY5

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-7744R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-7744R-CY5
Codice articolo locale: BOSSBS-7744R-CY5
Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7508R-A555

Anti-THSD1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-7508R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7508R-A555
Codice articolo locale: BOSSBS-7508R-A555
Descrizione: Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7508R-FITC

Anti-THSD1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-7508R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7508R-FITC
Codice articolo locale: BOSSBS-7508R-FITC
Descrizione: Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13110R-A750

Anti-ETFDH Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-13110R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13110R-A750
Codice articolo locale: BOSSBS-13110R-A750
Descrizione: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13632R-FITC

Anti-DLG5 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-13632R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13632R-FITC
Codice articolo locale: BOSSBS-13632R-FITC
Descrizione: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.
UOM: 1 * 100 µl
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