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Malonyl coenzyme A lithium salt ≥90%

Fornitore: Cayman Chemical
Descrizione: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

Image Unavailable-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Fornitore: Merck
Descrizione: Organic Standard, Malonyl-ʟ-carnitine lithium salt

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Cerulenin ≥98%, crystalline solid

Fornitore: Cayman Chemical
Descrizione: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-12952R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-12952R-A680
Codice articolo locale: BOSSBS-12952R-A680
Descrizione: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-12954R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-12954R-A680
Codice articolo locale: BOSSBS-12954R-A680
Descrizione: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-12952R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-12952R-A750
Codice articolo locale: BOSSBS-12952R-A750
Descrizione: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Codice catalogo: (BOSSBS-12954R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-12954R-A750
Codice articolo locale: BOSSBS-12954R-A750
Descrizione: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-500MG

Coenzyme A trilithium salt

Fornitore: Apollo Scientific
Descrizione: Coenzyme A trilithium salt

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4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Fornitore: Cayman Chemical
Descrizione: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

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Coenzyme A sodium salt hydrate ≥95%

Fornitore: Cayman Chemical
Descrizione: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

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Acetyl-Coenzyme A Trilithium Salt

Fornitore: Apollo Scientific
Descrizione: Acetyl-Coenzyme A Trilithium Salt

Certificati

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L(+)-Lithium lactate per sintesi, Sigma-Aldrich®

Fornitore: Merck
Descrizione: L(+)-Lithium lactate per sintesi, Sigma-Aldrich®

MSDS

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Riboflavin 5'-monophosphate sodium salt hydrate

Fornitore: Cayman Chemical
Descrizione: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Image Unavailable-8.20590.0025

Monoethyl fumarate lithium salt per sintesi

Codice catalogo: (8.20590.0025)
Fornitore: Merck
Codice articolo fornitore: 8.20590.0025
Codice articolo locale: MERC8.20590.0025
Descrizione: Monoethyl fumarate lithium salt per sintesi
UOM: 1 * 25 g
Image Unavailable-ENZOALX460003G010

Calcium pantothenate ≥98% (by HPLC)

Codice catalogo: (ENZOALX460003G010)
Fornitore: ENZO LIFE SCIENCES AG
Codice articolo fornitore: ALX460003G010
Codice articolo locale: ENZOALX460003G010
Descrizione: Precursor for coenzyme A biosynthesis.
UOM: 1 * 10 g

New Product


Image Unavailable-73885-10MG

Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Fornitore: Merck
Descrizione: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt

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