Hai cercato: L-Histidine-beta-naphthylamide

Fornitore: Apollo Scientific

Descrizione: L-Histidine-β-naphthylamide

Fornitore: TCI EUROPE

Descrizione: L-Leucine-2-naphthylamide hydrochloride ≥98.0% (by HPLC, titration analysis) 2-naphthylamine-free

Fornitore: Apollo Scientific

Descrizione: Pyr-βNA

Fornitore: MP Biomedicals

Descrizione: Soluble in methanol (50 mg/ml - clear, colourless solution). Soluble in water (50 mg/ml).

Fornitore: TCI EUROPE

Descrizione: beta-Alanyl-L-histidine

Fornitore: Thermo Scientific

Descrizione: CAS No.: 305-84-0

MSDS

Fornitore: Apollo Scientific

Descrizione: (S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid 97%

Codice catalogo: (BOSSBS-20594R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-20594R-A680

Codice articolo locale: BOSSBS-20594R-A680

Descrizione: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-20595R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-20595R-A680

Codice articolo locale: BOSSBS-20595R-A680

Descrizione: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-20594R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-20594R-A750

Codice articolo locale: BOSSBS-20594R-A750

Descrizione: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-20595R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-20595R-A750

Codice articolo locale: BOSSBS-20595R-A750

Descrizione: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidised low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalised and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL.

UOM: 1 * 100 µl

Promo

Fornitore: TCI EUROPE

Descrizione: 3-Hydroxy-N-(1-naphthyl)-2-naphthamide

Fornitore: Apollo Scientific

Descrizione: Naphthalene-2-carboxamide 98%

Codice catalogo: (PRSI55-271)

Fornitore: ProSci Inc.

Codice articolo fornitore: 55-271

Codice articolo locale: PRSI55-271

Descrizione: CARNS1 (EC 6.3.2.11), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).

UOM: 1 * 400 µl

New Product Promo

Codice catalogo: (TCIAH0319-25G)

Fornitore: TCI EUROPE

Codice articolo fornitore: H0319-25G

Codice articolo locale: TCIAH0319-25G

Descrizione: 3-Hydroxy-N-(2-naphthyl)-2-naphthamide ≥97.0% (by HPLC, titration analysis)

UOM: 1 * 25 g

Promo

Codice catalogo: (PRSI92-416)

Fornitore: ProSci Inc.

Codice articolo fornitore: 92-416

Codice articolo locale: PRSI92-416

Descrizione: Mouse cytosolic non-specific dipeptidase(CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyses a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyse carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumour suppressor in hepatocellular carcinoma (HCC) cells.

UOM: 1 * 50 µG

Promo