Hai cercato: Tonbo Biosciences

Codice catalogo: (70-1522-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-1522-U100

Codice articolo locale: TNBO70-1522-U100

Descrizione: Anti-CTLA4 Armenian Hamster Monoclonal Antibody [clone: UC10-4F10-11]

UOM: 1 * 100 µG

Promo

Fornitore: Tonbo Biosciences

Descrizione: The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Fornitore: Tonbo Biosciences

Descrizione: The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

Fornitore: Tonbo Biosciences

Descrizione: The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Codice catalogo: (70-0451-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0451-U100

Codice articolo locale: TNBO70-0451-U100

Descrizione: The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB and CD45RO.

UOM: 1 * 100 µG

Promo

Fornitore: Tonbo Biosciences

Descrizione: The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Fornitore: Tonbo Biosciences

Descrizione: The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Codice catalogo: (35-4321-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 35-4321-U100

Codice articolo locale: TNBO35-4321-U100

Descrizione: The 2A3 immunoglobulin is useful as an isotype-matched control. The 2A3 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2a antibodies.

UOM: 1 * 100 µG

Promo

Fornitore: Tonbo Biosciences

Descrizione: The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7. The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.

Fornitore: Tonbo Biosciences

Descrizione: The 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation. The 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.

Codice catalogo: (35-8015-U500)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 35-8015-U500

Codice articolo locale: TNBO35-8015-U500

Descrizione: Goat anti-Human IgA (alpha chain), F(ab')2 Fragment - Affinity Pure, FITC Conjugate

UOM: 1 * 0,5 mg

Promo

Codice catalogo: (30-8020-U500)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-8020-U500

Codice articolo locale: TNBO30-8020-U500

Descrizione: Goat anti-Human IgA (alpha chain), F(ab)'2 Fragment - Affinity Pure, Biotin Conjugate

UOM: 1 * 0,5 mg

Promo

Codice catalogo: (70-8030-M002)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-8030-M002

Codice articolo locale: TNBO70-8030-M002

Descrizione: Goat anti-Human IgM (mu chain) - Affinity Pure, min x w/human IgA + IgG

UOM: 1 * 2 mg

Promo

Codice catalogo: (30-8117-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-8117-M001

Codice articolo locale: TNBO30-8117-M001

Descrizione: Goat anti-Human IgA (alpha chain) - Affinity Pure, Biotin Conjugate, min x w/bovine, mouse, and rabbit serum proteins

UOM: 1 * 1 mg

Promo

Codice catalogo: (70-8042-M002)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-8042-M002

Codice articolo locale: TNBO70-8042-M002

Descrizione: Goat anti-Mouse IgG (H&L) - Affinity Pure

UOM: 1 * 2 mg

Promo

Codice catalogo: (70-8075-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-8075-M001

Codice articolo locale: TNBO70-8075-M001

Descrizione: Rabbit anti-Human IgM (mu chain) - Affinity Pure

UOM: 1 * 1 mg

Promo