Hai cercato: Tonbo Biosciences

Fornitore: Tonbo Biosciences

Descrizione: The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).

Codice catalogo: (72-8083-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 72-8083-M001

Codice articolo locale: TNBO72-8083-M001

Descrizione: Goat anti-Human IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/bovine, mouse or rabbit serum proteins

UOM: 1 * 1 mg

Promo

Codice catalogo: (35-8027-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 35-8027-M001

Codice articolo locale: TNBO35-8027-M001

Descrizione: Goat anti-Human IgE (epsilon chain) - Affinity Pure, FITC Conjugate, min x w/bovine, mouse or rabbit serum proteins

UOM: 1 * 1 mg

Promo

Codice catalogo: (30-8028-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-8028-M001

Codice articolo locale: TNBO30-8028-M001

Descrizione: Goat anti-Human IgM (mu chain) - Affinity Pure, Biotin Conjugate

UOM: 1 * 1 mg

Promo

Codice catalogo: (70-8024-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-8024-M001

Codice articolo locale: TNBO70-8024-M001

Descrizione: Goat anti-Human IgE (epsilon chain) - Affinity Pure, min x w/bovine, mouse or rabbit serum proteins

UOM: 1 * 1 mg

Promo

Codice catalogo: (50-8036-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 50-8036-M001

Codice articolo locale: TNBO50-8036-M001

Descrizione: Goat anti-Rabbit IgG, secondary antibody, conjugated toSureLight® R-Phycoerythrin

UOM: 1 * 1 mg

Promo

Codice catalogo: (72-8084-M001)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 72-8084-M001

Codice articolo locale: TNBO72-8084-M001

Descrizione: Donkey anti-Rabbit IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/bovine, chicken, goat, guinea pig, hamster, horse, human, mouse, rat or sheep

UOM: 1 * 1 mg

Promo

Fornitore: Tonbo Biosciences

Descrizione: The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.

Fornitore: Tonbo Biosciences

Descrizione: The SN5c antibody is specific for human CD10, a 100 kDa type II transmembrane protein also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA). In normal cells, it is expressed on early B and T lymphoid precursors, neutrophils and on various epithelia. CD10 is also expressed on several lymphoma cells including Burkitt�s, acute lymphoblastic, and follicular germinal center lymphomas. CD10 functions as an endopeptidase and is involved in B cell development, as well as a mediator of neutrophil inflammatory responses.

Fornitore: Tonbo Biosciences

Descrizione: The Human Basic B Lymphocyte backbone panel is a six-color combination of anti-human antibodies. This panel can serve as a backbone to identify the various B lymphocyte subsets, including naive, memory and plasma cells. This panel configuration leaves room for GFP or additional drop-in markers, if desired. Violet laser (405 nm) required for detection of CD45 violetFluoTM 450.

Fornitore: Tonbo Biosciences

Descrizione: The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

Fornitore: Tonbo Biosciences

Descrizione: The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).

Fornitore: Tonbo Biosciences

Descrizione: The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Codice catalogo: (70-5961-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-5961-U100

Codice articolo locale: TNBO70-5961-U100

Descrizione: The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.

UOM: 1 * 100 µG

Promo

Fornitore: Tonbo Biosciences

Descrizione: The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).

Fornitore: Tonbo Biosciences

Descrizione: The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.