Hai cercato: genome

Codice catalogo: (BOSSBS-6905R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-6905R-A555

Codice articolo locale: BOSSBS-6905R-A555

Descrizione: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-HRP

Codice articolo locale: BOSSBS-6089R-HRP

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4219R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-4219R-FITC

Codice articolo locale: BOSSBS-4219R-FITC

Descrizione: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].

UOM: 1 * 100 µl

Promo

Codice catalogo: (ABCAAB25146-100)

Fornitore: Abcam

Codice articolo fornitore: AB25146-100

Codice articolo locale: ABCAAB25146-100

Descrizione: Anti-Macrophage Specific Gene Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-6816R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-6816R-A350

Codice articolo locale: BOSSBS-6816R-A350

Descrizione: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-CY5.5

Codice articolo locale: BOSSBS-6089R-CY5.5

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-FITC

Codice articolo locale: BOSSBS-6089R-FITC

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-CY3

Codice articolo locale: BOSSBS-6089R-CY3

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-A647

Codice articolo locale: BOSSBS-6089R-A647

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6394R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-6394R-A350

Codice articolo locale: BOSSBS-6394R-A350

Descrizione: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6516R)

Fornitore: Bioss

Codice articolo fornitore: BS-6516R

Codice articolo locale: BOSSBS-6516R

Descrizione: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.

UOM: 1 * 100 µl

Promo

Codice catalogo: (USBIE3440-50A)

Fornitore: US Biological

Codice articolo fornitore: E3440-50A

Codice articolo locale: USBIE3440-50A

Descrizione: Anti-EBV-Induced Gene 3 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-6394R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-6394R-A680

Codice articolo locale: BOSSBS-6394R-A680

Descrizione: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6816R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-6816R-CY7

Codice articolo locale: BOSSBS-6816R-CY7

Descrizione: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6816R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6816R-CY5.5

Codice articolo locale: BOSSBS-6816R-CY5.5

Descrizione: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12290R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-12290R-HRP

Codice articolo locale: BOSSBS-12290R-HRP

Descrizione: The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif. RBMY (RBM, Y chromosome) encodes a germ-cell specific nuclear protein involved in spermatogenesis. The RBM gene family, including RBMY1A, RBMY1B, RBMY1D, RBMY1E, RBMY1F, RBMY1H and RBMY1J, is comprised of at least 30 genes and pseudogenes, found on both arms of the Y chromosome. RBM X, an ancestral X chromosome homolog of the RBMY gene, encodes hnRNP G, which is widely expressed, whereas the RBMY gene evolved a male-specific function in spermatogenesis. Micro-deletions of the AZFb region of the Y chromosome, which contains a number of RBMY genes, usually result in severe consequences for spermatogenesis. RBM expression is localized to the nuclei of germ cells and RBM interacts with Tra2beta. Tra2beta is a ubiquitous activator of pre-mRNA splicing, but is most highly expressed in testis, suggesting a role for RBM in Tra2beta-dependent splicing in spermatocytes. The human RBMX gene maps to chromosome Xq26 and the RBMY gene family is found on all mammalian Y chomosomes.

UOM: 1 * 100 µl

Promo