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Codice catalogo: (USBIM3886-75Y3)
Fornitore: US Biological
Codice articolo fornitore: M3886-75Y3
Codice articolo locale: USBIM3886-75Y3
Descrizione: Anti-MHC Class 1 Chain-related Gene A, B Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: 10F158]
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-11599R)
Fornitore: Bioss
Codice articolo fornitore: BS-11599R
Codice articolo locale: BOSSBS-11599R
Descrizione: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11600R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11600R-CY3
Codice articolo locale: BOSSBS-11600R-CY3
Descrizione: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11599R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11599R-CY3
Codice articolo locale: BOSSBS-11599R-CY3
Descrizione: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11207R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11207R-FITC
Codice articolo locale: BOSSBS-11207R-FITC
Descrizione: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6571R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-6571R-CY7
Codice articolo locale: BOSSBS-6571R-CY7
Descrizione: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Alternate splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6571R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-6571R-A488
Codice articolo locale: BOSSBS-6571R-A488
Descrizione: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Alternate splicing results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4140R)
Fornitore: Bioss
Codice articolo fornitore: BS-4140R
Codice articolo locale: BOSSBS-4140R
Descrizione: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6114R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6114R-CY5.5
Codice articolo locale: BOSSBS-6114R-CY5.5
Descrizione: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5592R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-5592R-A750
Codice articolo locale: BOSSBS-5592R-A750
Descrizione: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6248R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-6248R-A750
Codice articolo locale: BOSSBS-6248R-A750
Descrizione: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localised to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8076R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-8076R-A647
Codice articolo locale: BOSSBS-8076R-A647
Descrizione: ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8076R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-8076R-A750
Codice articolo locale: BOSSBS-8076R-A750
Descrizione: ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8076R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-8076R-CY7
Codice articolo locale: BOSSBS-8076R-CY7
Descrizione: ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localised, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterised by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognised for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localised genes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8076R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-8076R-A488
Codice articolo locale: BOSSBS-8076R-A488
Descrizione: ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2365R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-2365R-CY5
Codice articolo locale: BOSSBS-2365R-CY5
Descrizione: This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. [provided by RefSeq].
UOM: 1 * 100 µl


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