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Image Unavailable-BOSSBS-3251R-A750

Anti-5-Lipoxygenase Ser271 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-3251R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R-A750
Codice articolo locale: BOSSBS-3251R-A750
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyses the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-TCIAD5585-1G

Diethyl 2,4-Dimethyl-5-[(triisopropylsilyl)methylene]-1,3-cyclopentadiene-1,3-dicarboxylate cis- and trans-mixture ≥93.0% (by HPLC)

Codice catalogo: (TCIAD5585-1G)
Fornitore: TCI
Codice articolo fornitore: D5585-1G
Codice articolo locale: TCIAD5585-1G
Descrizione: Diethyl 2,4-Dimethyl-5-[(triisopropylsilyl)methylene]-1,3-cyclopentadiene-1,3-dicarboxylate cis- and trans-mixture ≥93.0% (by HPLC)
UOM: 1 * 1 g
Image Unavailable-BOSSBS-4281R-CY5.5

Anti-USP7 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-4281R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-4281R-CY5.5
Codice articolo locale: BOSSBS-4281R-CY5.5
Descrizione: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4281R-A750

Anti-HAUSP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-4281R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-4281R-A750
Codice articolo locale: BOSSBS-4281R-A750
Descrizione: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilises p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilisation and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilising the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
UOM: 1 * 100 µl
Image Unavailable-APOSOR4507-25G

Dietil fumarato 95%

Codice catalogo: (APOSOR4507-25G)
Fornitore: Apollo Scientific
Codice articolo fornitore: OR4507-25G
Codice articolo locale: APOSOR4507-25G
Descrizione: Dietil fumarato 95%
UOM: 1 * 25 g
Product Image-ACRO216270010

Methyl-5-norbornene-2,3-dicarboxylic anhydride (mixture of isomers) 95%

Fornitore: Thermo Fisher Scientific
Descrizione: Appearance: Clear light yellow Viscous liquid

MSDS

Image Unavailable-BOSSBS-13048R-A680

Anti-ECH1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-13048R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-13048R-A680
Codice articolo locale: BOSSBS-13048R-A680
Descrizione: ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13048R-HRP

Anti-ECH1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-13048R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-13048R-HRP
Codice articolo locale: BOSSBS-13048R-HRP
Descrizione: ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13048R

Anti-ECH1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-13048R)
Fornitore: Bioss
Codice articolo fornitore: BS-13048R
Codice articolo locale: BOSSBS-13048R
Descrizione: ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
UOM: 1 * 100 µl
Image Unavailable-TCIAC2506-5G

Z-Hyp-OH ≥98.0% (by HPLC, titration analysis)

Fornitore: TCI
Descrizione: Z-Hyp-OH ≥98.0% (by HPLC, titration analysis)

Image Unavailable-BOSSBS-3251R-CY5.5

Anti-ALOX5 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-3251R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R-CY5.5
Codice articolo locale: BOSSBS-3251R-CY5.5
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3251R-CY3

Anti-ALOX5 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-3251R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R-CY3
Codice articolo locale: BOSSBS-3251R-CY3
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3251R-A488

Anti-ALOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-3251R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R-A488
Codice articolo locale: BOSSBS-3251R-A488
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3251R

Anti-ALOX5 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-3251R)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R
Codice articolo locale: BOSSBS-3251R
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3251R-A555

Anti-ALOX5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-3251R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-3251R-A555
Codice articolo locale: BOSSBS-3251R-A555
Descrizione: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM: 1 * 100 µl
Image Unavailable-APOSPC7664-100G

4-(Trifluoromethyl)cinnamic acid 98%

Fornitore: Apollo Scientific
Descrizione: 4-(Trifluoromethyl)cinnamic acid 98%

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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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