Hai cercato: Tyrphostin+B7

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Member of the tyrphostin family of tyrosine kinase inhibitors. Selective inhibitor of the PDGF receptor kinase (IC50=20µM) vs. the EGF receptor kinase (IC50=820µM). Inhibits PDGF-induced mitogenesis in human bone marrow fibroblasts.

New Product

Fornitore: Apollo Scientific

Descrizione: Tyrphostin 1 95%

Codice catalogo: (ENZOALX270141M025)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: ALX270141M025

Codice articolo locale: ENZOALX270141M025

Descrizione: Tyrphostin AG 527 ≥98% (by HPLC)

UOM: 1 * 25 mg

New Product Promo

Fornitore: TCI EUROPE

Descrizione: Tyrphostin RG 14620 ≥98.0% (by HPLC)

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Tyrphostin 9 is a selective inhibitor of the PDGF receptor tyrosine kinase (IC50=1.2 µM). It is also a potent (10 nM) uncoupler of oxidative phosphorylation.

New Product

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

New Product

Fornitore: TCI EUROPE

Descrizione: Tyrphostin A23 ≥98.0% (by GC)

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.

New Product

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: An inactive tyrphostin, which may be used as a negative control.

New Product

Fornitore: TCI EUROPE

Descrizione: Tyrphostin A9 ≥98.0% (by GC)

Fornitore: TCI EUROPE

Descrizione: Tyrphostin 1 ≥98.0% (by GC)

Codice catalogo: (ENZOBMLEI1870005)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: BMLEI1870005

Codice articolo locale: ENZOBMLEI1870005

Descrizione: A potent inhibitor of EGF receptor kinase activity (IC50=3 µM).

UOM: 1 * 5 mg

New Product Promo

Fornitore: TCI EUROPE

Descrizione: Tyrphostin AG 835 ≥98.0% (by HPLC)

Codice catalogo: (ENZOBMLEI1910010)

Fornitore: ENZO LIFE SCIENCES AG

Codice articolo fornitore: BMLEI1910010

Codice articolo locale: ENZOBMLEI1910010

Descrizione: A potent inhibitor of EGF receptor kinase activity (IC50=35 µM).

UOM: 1 * 10 mg

New Product Promo

Codice catalogo: (TCIAT2944-25MG)

Fornitore: TCI EUROPE

Codice articolo fornitore: T2944-25MG

Codice articolo locale: TCIAT2944-25MG

Descrizione: Tyrphostin AG 1478 ≥98.0% (by HPLC)

UOM: 1 * 25 mg

Promo

Fornitore: Apollo Scientific

Descrizione: MAPK/ERK Signalling Pathway