Tyrphostin AG 1024 ≥98% (by HPLC and UV method)
Fornitore: ENZO LIFE SCIENCES AG
Synonyms:
2-(3-Bromo-5-(tert-butyl)-4-hydroxybenzylidene)malononitrile, AG1024
Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.
- IGF-1 inhibitor
Yellow powder.
Soluble in acetonitrile (5mg/ml), DMSO (8mg/ml), dichloromethane (23mg/ml) or methanol (5mg/ml); insoluble in 100% ethanol.
Formula:
C₁₄H₁₃BrN₂O Peso molecolare: 305,2 g/mol Temperatura di stoccaggio: Congelamento |
MDL Number:
MFCD02179365 CAS Number: 65678-07-1 |
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