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Fornitore: TCI EUROPE
Descrizione: Thymine ≥98.0% (by HPLC, titration analysis)

Fornitore: Thermo Scientific
Descrizione: Thymine 99%

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Codice catalogo: (APOSBIMN2031-1G)
Fornitore: Apollo Scientific
Codice articolo fornitore: BIMN2031-1G
Codice articolo locale: APOSBIMN2031-1G
Descrizione: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (2’-FANA-T) ≥95%
UOM: 1 * 1 g


Fornitore: Thermo Scientific
Descrizione: Thymine 97%
Codice catalogo: (PHR1345-250MG)
Fornitore: Merck
Codice articolo fornitore: PHR1345-250MG
Codice articolo locale: SUPLPHR1345-250MG
Descrizione: Organic Standard, Thymine(Zidovudine Related Compound C)
UOM: 1 * 250 mg


Codice catalogo: (TCIAA2073-25G)
Fornitore: TCI EUROPE
Codice articolo fornitore: A2073-25G
Codice articolo locale: TCIAA2073-25G
Descrizione: 1-(3,5-Anhydro-2-deoxy-β-D-threo-pentofuranosyl)thymine ≥98.0% (by HPLC, titration analysis)
UOM: 1 * 25 g


Fornitore: TCI EUROPE
Descrizione: Timidina (2'-Deossitimidina) ≥98.0% (by HPLC, titration analysis)

Codice catalogo: (BOSSBS-8288R)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R
Codice articolo locale: BOSSBS-8288R
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2950R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-2950R-CY7
Codice articolo locale: BOSSBS-2950R-CY7
Descrizione: Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2950R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-2950R-CY5
Codice articolo locale: BOSSBS-2950R-CY5
Descrizione: Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8288R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R-CY5
Codice articolo locale: BOSSBS-8288R-CY5
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8288R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R-CY3
Codice articolo locale: BOSSBS-8288R-CY3
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8288R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R-A350
Codice articolo locale: BOSSBS-8288R-A350
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2950R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-2950R-A750
Codice articolo locale: BOSSBS-2950R-A750
Descrizione: Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8288R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R-FITC
Codice articolo locale: BOSSBS-8288R-FITC
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterized by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8288R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-8288R-A680
Codice articolo locale: BOSSBS-8288R-A680
Descrizione: Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (5-FU) pathway and is involved in the efficacy and toxicity of 5-FU. Variations in DPYD concentration may arise from alterations at the transcriptional level of the dihydropyrimidine dehydrogenase gene. Specifically, hypermethylation of the DPYD promoter downregulates dihydropyrimidine dehydrogenase expression. Deficient DPYD alleles may constitute a risk factor for severe toxicity following treatment with 5-FU.Involvement in disease:Defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency (DPYD deficiency) ; also known as hereditary thymine-uraciluria or familial pyrimidinemia. DPYD deficiency is a disease characterised by persistent urinary excretion of excessive amounts of uracil, thymine and 5-hydroxymethyluracil. Patients suffering from this disease show a severe reaction to the anticancer drug 5-fluorouracil. This reaction includes stomatitis, Leukopenia, thrombocytopenia, hair loss, diarrhea, fever, marked weight loss, cerebellar ataxia, and neurologic symptoms, progressing to semicoma.
UOM: 1 * 100 µl


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