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SKI-II ≥95%, crystalline solid

Fornitore: Cayman Chemical
Descrizione: Sphingosine kinase isoforms, SPHK 1 and SPHK 2, catalyse the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. Sphingosine kinase inhibitor 2 (SPHK I<sub>2</sub>) is a potent, selective inhibitor of SPHK 1 with anti-proliferative activity.

Product Image-PRSI27-539

Anti-SNW1 Rabbit Polyclonal Antibody

Codice catalogo: (PRSI27-539)
Fornitore: ProSci Inc.
Codice articolo fornitore: 27-539
Codice articolo locale: PRSI27-539
Descrizione: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
UOM: 1 * 50 µG

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Image Unavailable-BOSSBS-1684R-A750

Anti-C-SKI/v-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-1684R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-A750
Codice articolo locale: BOSSBS-1684R-A750
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-A680

Anti-C-SKI/v-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-1684R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-A680
Codice articolo locale: BOSSBS-1684R-A680
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-CY3

Anti-SKI Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-1684R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-CY3
Codice articolo locale: BOSSBS-1684R-CY3
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-A350

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-1684R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-A350
Codice articolo locale: BOSSBS-1684R-A350
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-USBIS1013-89Z3

Anti-SKI Mouse Monoclonal Antibody

Codice catalogo: (USBIS1013-89Z3)
Fornitore: US Biological
Codice articolo fornitore: S1013-89Z3
Codice articolo locale: USBIS1013-89Z3
Descrizione: Anti-SKI Mouse Monoclonal Antibody
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-1684R-CY5

Anti-SKI Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-1684R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-CY5
Codice articolo locale: BOSSBS-1684R-CY5
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-HRP

Anti-SKI Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-1684R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-HRP
Codice articolo locale: BOSSBS-1684R-HRP
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-USBIS1013-89W

Anti-Ski-like Protein Rabbit Polyclonal Antibody

Codice catalogo: (USBIS1013-89W)
Fornitore: US Biological
Codice articolo fornitore: S1013-89W
Codice articolo locale: USBIS1013-89W
Descrizione: Anti-Ski-like Protein Rabbit Polyclonal Antibody
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-1684R-CY5.5

Anti-SKI Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-1684R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-CY5.5
Codice articolo locale: BOSSBS-1684R-CY5.5
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-USBI145990

Anti-SKI Rabbit Polyclonal Antibody

Codice catalogo: (USBI145990)
Fornitore: US Biological
Codice articolo fornitore: 145990
Codice articolo locale: USBI145990
Descrizione: Anti-SKI Rabbit Polyclonal Antibody
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-1684R-A647

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-1684R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-A647
Codice articolo locale: BOSSBS-1684R-A647
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-USBIS1013-89V

Anti-SKI Rabbit Polyclonal Antibody

Codice catalogo: (USBIS1013-89V)
Fornitore: US Biological
Codice articolo fornitore: S1013-89V
Codice articolo locale: USBIS1013-89V
Descrizione: Anti-SKI Rabbit Polyclonal Antibody
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-1684R-CY7

Anti-SKI Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-1684R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-CY7
Codice articolo locale: BOSSBS-1684R-CY7
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1684R-A488

Anti-SKI Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-1684R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-1684R-A488
Codice articolo locale: BOSSBS-1684R-A488
Descrizione: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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