Hai cercato: N-Stearoyl-D-erythro-sphingosine

Codice catalogo: (BOSSBS-2652R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-2652R-CY5

Codice articolo locale: BOSSBS-2652R-CY5

Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2652R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-2652R-FITC

Codice articolo locale: BOSSBS-2652R-FITC

Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].

UOM: 1 * 100 µl

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: 1,4-Ditioeritritolo ≥99%

MSDS Certificati

Codice catalogo: (BOSSBS-5018R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-5018R-CY5.5

Codice articolo locale: BOSSBS-5018R-CY5.5

Descrizione: ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5018R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-5018R-A350

Codice articolo locale: BOSSBS-5018R-A350

Descrizione: ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-FITC

Codice articolo locale: BOSSBS-1635R-FITC

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6021R)

Fornitore: Bioss

Codice articolo fornitore: BS-6021R

Codice articolo locale: BOSSBS-6021R

Descrizione: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

UOM: 1 * 100 µl

Promo

Fornitore: TCI

Descrizione: 1,4-Ditioeritritolo ≥98.0% (by titrimetric analysis)

Codice catalogo: (APOSBISN0008-5MG)

Fornitore: Apollo Scientific

Codice articolo fornitore: BISN0008-5MG

Codice articolo locale: APOSBISN0008-5MG

Descrizione: Pentostatin can inhibit adenosine deaminase irreversibly with Ki of 2.5 pM, as an antineoplastic anti-metabolite used in the treatment of several forms of leukemia.

UOM: 1 * 5 mg

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: L-Biopterin ≥98%

Codice catalogo: (BOSSBS-2652R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-2652R-A488

Codice articolo locale: BOSSBS-2652R-A488

Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0136R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-0136R-HRP

Codice articolo locale: BOSSBS-0136R-HRP

Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-0136R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-0136R-A488

Codice articolo locale: BOSSBS-0136R-A488

Descrizione: GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-CY5.5

Codice articolo locale: BOSSBS-1635R-CY5.5

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2652R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-2652R-A647

Codice articolo locale: BOSSBS-2652R-A647

Descrizione: Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].

UOM: 1 * 100 µl

Promo

Fornitore: Apollo Scientific

Descrizione: Reagent for maintaining -SH groups in reduced state.