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Hai cercato: N-Palmitoyl+phosphatidylethanolamine


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Codice catalogo: (BOSSBS-11663R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11663R-CY3
Codice articolo locale: BOSSBS-11663R-CY3
Descrizione: Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.
UOM: 1 * 100 µl


Fornitore: Thermo Fisher Scientific
Descrizione: 6-O-Palmitoyl-L-ascorbic acid ≥99%
Codice catalogo: (BOSSBS-0759R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-0759R-A680
Codice articolo locale: BOSSBS-0759R-A680
Descrizione: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyses the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5204R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-5204R-A350
Codice articolo locale: BOSSBS-5204R-A350
Descrizione: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5204R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-5204R-HRP
Codice articolo locale: BOSSBS-5204R-HRP
Descrizione: E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5198R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-5198R-FITC
Codice articolo locale: BOSSBS-5198R-FITC
Descrizione: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
UOM: 1 * 100 µl


Codice catalogo: (TCIAA0540-25G)
Fornitore: TCI
Codice articolo fornitore: A0540-25G
Codice articolo locale: TCIAA0540-25G
Descrizione: 6-O-Palmitoyl-L-ascorbic acid ≥97.0% (by titrimetric analysis)
UOM: 1 * 25 g


Codice catalogo: (BOSSBS-4009R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-4009R-A555
Codice articolo locale: BOSSBS-4009R-A555
Descrizione: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
UOM: 1 * 100 µl


Fornitore: Thermo Fisher Scientific
Descrizione: Palmitoyl chloride ≥98%
Fornitore: Merck
Descrizione: Organic Standard, Palmitoyl-ʟ-carnitine

Fornitore: TCI
Descrizione: Palmitoyl chloride ≥97.0% (by GC, titration analysis)

Fornitore: Apollo Scientific
Descrizione: A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphate & stimulates ceramide-activated protein kinase.

Codice catalogo: (TCIAP2694-250MG)
Fornitore: TCI
Codice articolo fornitore: P2694-250MG
Codice articolo locale: TCIAP2694-250MG
Descrizione: 1-Palmitoyl-sn-glycero-3-phosphocholine ≥98.0% (by HPLC, titration analysis)
UOM: 1 * 250 mg


Fornitore: Thermo Fisher Scientific
Descrizione: 6-O-Palmitoyl-L-ascorbic acid, meets analytical specification of Ph. Eur., USP
Codice catalogo: (BOSSBS-4009R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-4009R-HRP
Codice articolo locale: BOSSBS-4009R-HRP
Descrizione: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4009R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-4009R-A350
Codice articolo locale: BOSSBS-4009R-A350
Descrizione: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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