Hai cercato: N-Palmitoyl+phosphatidylethanolamine

Fornitore: ENZO LIFE SCIENCES

Descrizione: Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.

New Product

Codice catalogo: (BOSSBS-7948R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-7948R-CY5

Codice articolo locale: BOSSBS-7948R-CY5

Descrizione: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glyceroN-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7948R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-7948R-A647

Codice articolo locale: BOSSBS-7948R-A647

Descrizione: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glyceroN-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7948R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-7948R-HRP

Codice articolo locale: BOSSBS-7948R-HRP

Descrizione: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glyceroN-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4013R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-4013R-CY3

Codice articolo locale: BOSSBS-4013R-CY3

Descrizione: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

UOM: 1 * 100 µl

Promo

Fornitore: Merck

Descrizione: Palmitoyl chloride per sintesi, Sigma-Aldrich®

MSDS

Codice catalogo: (BOSSBS-7075R)

Fornitore: Bioss

Codice articolo fornitore: BS-7075R

Codice articolo locale: BOSSBS-7075R

Descrizione: Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase.

UOM: 1 * 100 µl

Promo

Fornitore: Apollo Scientific

Descrizione: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 98+%

Codice catalogo: (USBIP9054-78P)

Fornitore: US Biological

Codice articolo fornitore: P9054-78P

Codice articolo locale: USBIP9054-78P

Descrizione: Anti-PEBP4, Phosphatidylethanolamine Binding Protein 4 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-7948R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-7948R-A750

Codice articolo locale: BOSSBS-7948R-A750

Descrizione: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glyceroN-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.

UOM: 1 * 100 µl

Promo

Codice catalogo: (TCIAD4251-250MG)

Fornitore: TCI

Codice articolo fornitore: D4251-250MG

Codice articolo locale: TCIAD4251-250MG

Descrizione: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine ≥98.0% (by titrimetric analysis)

UOM: 1 * 250 mg

Promo

Codice catalogo: (BOSSBS-7948R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-7948R-A555

Codice articolo locale: BOSSBS-7948R-A555

Descrizione: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glyceroN-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5198R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-5198R-CY3

Codice articolo locale: BOSSBS-5198R-CY3

Descrizione: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4013R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-4013R-A350

Codice articolo locale: BOSSBS-4013R-A350

Descrizione: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11663R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-11663R-FITC

Codice articolo locale: BOSSBS-11663R-FITC

Descrizione: Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.

UOM: 1 * 100 µl

Promo

Fornitore: USP

Descrizione: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.