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Codice catalogo: (BOSSBS-13479R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13479R-A750
Codice articolo locale: BOSSBS-13479R-A750
Descrizione: GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate. A member of the sulfatase family, GNS assists in the catabolism of heparin, and binds calcium as a cofactor. GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), which is characterized by mild somatic disease and severe degeneration of the central nervous system. Subject to post-translational internal peptidase cleavage, GNS is encoded by a gene mapping to human chromosome 12q14.2 and mouse chromosome 10 D2.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13479R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-13479R-A555
Codice articolo locale: BOSSBS-13479R-A555
Descrizione: GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate. A member of the sulfatase family, GNS assists in the catabolism of heparin, and binds calcium as a cofactor. GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), which is characterized by mild somatic disease and severe degeneration of the central nervous system. Subject to post-translational internal peptidase cleavage, GNS is encoded by a gene mapping to human chromosome 12q14.2 and mouse chromosome 10 D2.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7755R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-7755R-HRP
Codice articolo locale: BOSSBS-7755R-HRP
Descrizione: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Tissue specificity: Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.
UOM: 1 * 100 µl


Codice catalogo: (MILXMIACTUB01)
Fornitore: Merck
Codice articolo fornitore: MIACTUB01
Codice articolo locale: MILXMIACTUB01
Descrizione: <p>The silicon tubing is an additional accessory of the Microfil<sup>®</sup> filtration system. The Microfil<sup>®</sup> filtration system is a simple and reliable solution for routine microbiological testing. The push-fit design of the Microfil<sup>®</sup> funnels seals tightly to manifold supports without the need for clamps or O-rings. The tube is used to connect the pump to the manifold or filtration apparatus using the Tee connectors. The tubing is autoclavable, 5 m long, with an internal diameter of 9,5 mm.</p>
UOM: 1 * 1 pezzi

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Codice catalogo: (BOSSBS-7755R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7755R-A555
Codice articolo locale: BOSSBS-7755R-A555
Descrizione: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Tissue specificity: Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.
UOM: 1 * 100 µl


Codice catalogo: (PRSI55-254)
Fornitore: ProSci Inc.
Codice articolo fornitore: 55-254
Codice articolo locale: PRSI55-254
Descrizione: The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
UOM: 1 * 400 µl


Codice catalogo: (PRSI91-356)
Fornitore: ProSci Inc.
Codice articolo fornitore: 91-356
Codice articolo locale: PRSI91-356
Descrizione: Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.
UOM: 1 * 50 µG


Codice catalogo: (PRSI91-738)
Fornitore: ProSci Inc.
Codice articolo fornitore: 91-738
Codice articolo locale: PRSI91-738
Descrizione: CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
UOM: 1 * 50 µG


Fornitore: EDWARDS HIGH VACUUM METTLER
Descrizione: ATEX RV pumps have an external ATEX classification of Ex II 2G IIC T4 or Ex II 2G IIB T4 and internal ATEX classification Ex II 3G c IIB T4. They are suitable for use in potentially explosive atmospheres such as hazardous area pumping. They are supplied with the gas ballast port which must be fitted with an inert gas purge while pumping flammable gasses or vapours to dilute such gases or vapours below the lower explosive limit.

Codice catalogo: (BSBTPB9193)
Fornitore: Boster Bio
Codice articolo fornitore: PB9193
Codice articolo locale: BSBTPB9193
Descrizione: Polyclonal antibody for FGFR 4/FGFR4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. FGFR 4/FGFR4 information: Molecular Weight: 87954 MW; Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane; Tissue Specificity: Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-11243R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-11243R-A555
Codice articolo locale: BOSSBS-11243R-A555
Descrizione: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11243R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-11243R-CY7
Codice articolo locale: BOSSBS-11243R-CY7
Descrizione: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2960R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-2960R-A750
Codice articolo locale: BOSSBS-2960R-A750
Descrizione: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterised by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7755R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-7755R-A647
Codice articolo locale: BOSSBS-7755R-A647
Descrizione: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.Tissue specificity: Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13479R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13479R-A488
Codice articolo locale: BOSSBS-13479R-A488
Descrizione: GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate. A member of the sulfatase family, GNS assists in the catabolism of heparin, and binds calcium as a cofactor. GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), which is characterized by mild somatic disease and severe degeneration of the central nervous system. Subject to post-translational internal peptidase cleavage, GNS is encoded by a gene mapping to human chromosome 12q14.2 and mouse chromosome 10 D2.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11243R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-11243R-A350
Codice articolo locale: BOSSBS-11243R-A350
Descrizione: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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