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Image Unavailable-BOSSBS-6737R-HRP

Anti-ARMC10 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-6737R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-HRP
Codice articolo locale: BOSSBS-6737R-HRP
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6737R-A647

Anti-ARMC10 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-6737R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-A647
Codice articolo locale: BOSSBS-6737R-A647
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6737R-CY5

Anti-ARMC10 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-6737R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-CY5
Codice articolo locale: BOSSBS-6737R-CY5
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1180R-A680

Anti-RhoA/C Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-1180R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-1180R-A680
Codice articolo locale: BOSSBS-1180R-A680
Descrizione: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibres. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilisation of microtubules at the cell cortex. It controls the localisation of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localisation of the MACF1 to the cell membrane, which is required for microtubule capture and stabilisation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13356R-A350

Anti-GOLGB1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-13356R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-13356R-A350
Codice articolo locale: BOSSBS-13356R-A350
Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13356R-FITC

Anti-GOLGB1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-13356R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13356R-FITC
Codice articolo locale: BOSSBS-13356R-FITC
Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4100R-A680

Anti-DLP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-4100R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-4100R-A680
Codice articolo locale: BOSSBS-4100R-A680
Descrizione: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
UOM: 1 * 100 µl
Product Image-786-250

Protein fractionation kit, FOCUS™ signal proteins

Codice catalogo: (786-250)
Fornitore: G-Biosciences
Codice articolo fornitore: 786-250
Codice articolo locale: GENO786-250
Descrizione: Lipid rafts are membrane microdomains that are enriched in caveolin, cholesterol, glycolipids, sphingolipids and glycosyl-phosphatidylinositol. Lipid rafts are also known as detergent-insoluble glycolipid-enriched complexes (GEMs) or DIGs. Many signalling proteins, including glycosylphosphatidylinositol (GPI)-anchored proteins, doubly-acylated tyrosine kinases of the Src family, and transmembrane proteins, are located in lipid rafts. Lipid raft localised proteins have been shown to be involved in intracellular membrane trafficking and signalling.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-6916R-CY5.5

Anti-RABX5 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-6916R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6916R-CY5.5
Codice articolo locale: BOSSBS-6916R-CY5.5
Descrizione: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2379R-A488

Anti-LAMP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-2379R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-2379R-A488
Codice articolo locale: BOSSBS-2379R-A488
Descrizione: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13689R-A488

Anti-MPP2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-13689R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13689R-A488
Codice articolo locale: BOSSBS-13689R-A488
Descrizione: MPP2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13689R-FITC

Anti-MPP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-13689R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13689R-FITC
Codice articolo locale: BOSSBS-13689R-FITC
Descrizione: MPP2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
UOM: 1 * 100 µl
Image Unavailable-72015-50MG

Sodium tetrakis[3,5-bis(1,1,1,3,3,3-hexafluoro-2-methoxy-2-propyl)phenyl]borate trihydrate, Selectophore™ ionophore, Supelco®

Codice catalogo: (72015-50MG)
Fornitore: Merck
Codice articolo fornitore: 72015-50MG
Codice articolo locale: SUPL72015-50MG
Descrizione: Lipophilic ion exchanger for ion-selective membrane electrodes.
UOM: 1 * 50 mg
Product Image-786-09APT

picoLUCENT™ PLUS-AP kit

Fornitore: G-Biosciences
Descrizione: The picoLUCENT™ PLUS-HRP kit is based on an ultra sensitive luminol substrate that produces chemiluminescence upon reaction with alkaline phosphatase. The chemiluminescence light emission can be recorded by a short exposure to autoradiography films.

Product Image-734-5076

Bottle top vacuum filtration units, Rapid-Flow™ Nalgene®

Fornitore: Thermo Fisher Scientific
Descrizione: <p>Rapid-Flow™ single use bottle tops with PES membrane and PS funnel. Filters screw onto glass media bottles with 33 or 45 mm neck size. They feature the exclusive Rapid-Flow support column design, providing fast flow rates and high throughput.</p>

Environmentally Preferable Promo

Image Unavailable-BOSSBS-1970R-A647

Anti-LAMP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-1970R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-1970R-A647
Codice articolo locale: BOSSBS-1970R-A647
Descrizione: Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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