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Fornitore: G-Biosciences
Descrizione: The picoLUCENT™ PLUS-HRP kit is based on an ultra sensitive luminol substrate that produces chemiluminescence upon reaction with alkaline phosphatase. The chemiluminescence light emission can be recorded by a short exposure to autoradiography films.

Codice catalogo: (BOSSBS-1343R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1343R-HRP
Codice articolo locale: BOSSBS-1343R-HRP
Descrizione: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
UOM: 1 * 100 µl


Codice catalogo: (ABCAAB310822-100UL)
Fornitore: Abcam
Codice articolo fornitore: AB310822-100UL
Codice articolo locale: ABCAAB310822-100UL
Descrizione: APC Rabbit monoclonal [EPR3633(2)] to Calnexin - ER Membrane Marker.
UOM: 1 * 100 µl


Fornitore: Merck
Descrizione: Sterile Millex filter units are available in a larger 33 mm housing with MCE membranes.

Codice catalogo: (BOSSBS-2673R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-2673R-HRP
Codice articolo locale: BOSSBS-2673R-HRP
Descrizione: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6737R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-CY3
Codice articolo locale: BOSSBS-6737R-CY3
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6737R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-A555
Codice articolo locale: BOSSBS-6737R-A555
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6737R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-6737R-A350
Codice articolo locale: BOSSBS-6737R-A350
Descrizione: SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1528R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-1528R-CY3
Codice articolo locale: BOSSBS-1528R-CY3
Descrizione: Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11261R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-11261R-CY7
Codice articolo locale: BOSSBS-11261R-CY7
Descrizione: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11261R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11261R-FITC
Codice articolo locale: BOSSBS-11261R-FITC
Descrizione: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11261R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11261R-A680
Codice articolo locale: BOSSBS-11261R-A680
Descrizione: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalisation upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11261R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-11261R-A488
Codice articolo locale: BOSSBS-11261R-A488
Descrizione: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11352R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11352R-A647
Codice articolo locale: BOSSBS-11352R-A647
Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11352R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11352R-HRP
Codice articolo locale: BOSSBS-11352R-HRP
Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3924R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-3924R-A488
Codice articolo locale: BOSSBS-3924R-A488
Descrizione: This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


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