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Product Image-MILFACR5000PA

Amicon® Pro Affinity Concentration Kit, Ultra-0.5 Device

Fornitore: Merck
Descrizione: A centrifugal tool for purifying and concentrating His-tagged proteins, GSH-tagged proteins and antibodies.

Product Image-701-0173

Groundwater sampling capsules, Polycap™ GW, Whatman™

Fornitore: Whatman products (Cytiva)
Descrizione: These Polycap™ GW (Ground Water) capsule filters are specifically designed for sample preparation of ground water samples for dissolved metals analysis. The in-line design with stepped hose barbs and hydrophilic polyethersulfone (PES) membrane make it easy to use for field sampling.

Image Unavailable-BOSSBS-13689R-CY7

Anti-MPP2 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-13689R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-13689R-CY7
Codice articolo locale: BOSSBS-13689R-CY7
Descrizione: MPP2 (Palmitoylated membrane protein 2) is a member of a family of membrane associated proteins termed MAGUKs (membrane associated guanylate kinase homologs). These proteins interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6688R-A680

Anti-SCN8A Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-6688R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6688R-A680
Codice articolo locale: BOSSBS-6688R-A680
Descrizione: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6264R-CY5

Anti-EMP2 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-6264R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-6264R-CY5
Codice articolo locale: BOSSBS-6264R-CY5
Descrizione: EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
UOM: 1 * 100 µl
Product Image-BSENR-1686-500

Anti-Nicastrin, N-terminal domain Rabbit Polyclonal Antibody

Codice catalogo: (BSENR-1686-500)
Fornitore: Biosensis
Codice articolo fornitore: R-1686-500
Codice articolo locale: BSENR-1686-500
Descrizione: Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.
UOM: 1 * 500 µG
Image Unavailable-BOSSBS-6072R-A647

Anti-MCC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-6072R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-6072R-A647
Codice articolo locale: BOSSBS-6072R-A647
Descrizione: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11511R-A488

Anti-BBS9 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-11511R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-11511R-A488
Codice articolo locale: BOSSBS-11511R-A488
Descrizione: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2540R-A750

Anti-GLUT12 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-2540R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-2540R-A750
Codice articolo locale: BOSSBS-2540R-A750
Descrizione: GLUT12 belongs to a family of transporters that catalyse the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.
UOM: 1 * 100 µl
Product Image-MILFUFC703008

Centrifugal filters, Centricon® Plus-70

Fornitore: Merck
Descrizione: Centrifugal filter units concentrate samples in the range of 15 ml to 70 ml. The large dead stop volume of 350 µl prevents spinning samples to dryness. It has two vertical regenerated cellulose membranes for fast, efficient tangential flow.

Image Unavailable-BOSSBS-11511R-A680

Anti-BBS9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-11511R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11511R-A680
Codice articolo locale: BOSSBS-11511R-A680
Descrizione: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localisation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9393R-CY7

Anti-VPRBP Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-9393R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-9393R-CY7
Codice articolo locale: BOSSBS-9393R-CY7
Descrizione: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9576R-CY5

Anti-CPNE6 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-9576R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-9576R-CY5
Codice articolo locale: BOSSBS-9576R-CY5
Descrizione: Copine 6 is a 557 amino acid member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Arabidopsis thaliana mutants lacking copine proteins exhibit reduced cell number and smaller cell size, effects which may be due to a defect in vesicle fusion or transport. Copine 6 contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 6 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Copine 6 may also play a role in synaptic plasticity.
UOM: 1 * 100 µl
Product Image-514-0639

Dialysis membrane tubing, Biotech RC

Fornitore: Spectrum Laboratories
Descrizione: Biotech RC (Regenerated Cellulose) dialysis tubing is crafted from a regeneration process that yields superior temperature tolerances and chemical compatibilities with the same high purity and selectivity as Biotech CE. RC membrane can tolerate concentrated-weak acids & bases, dilute-strong acids and bases, most alcohols and some mild or dilute organic solvents. Exposure to strong polar or organic solvents may damage RC membranes. Use with pH 2 - 12 and temperature 4 - 60 °C.

Image Unavailable-BOSSBS-11395R-HRP

Anti-VAMP8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-11395R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11395R-HRP
Codice articolo locale: BOSSBS-11395R-HRP
Descrizione: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11395R-CY7

Anti-VAMP8 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-11395R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-11395R-CY7
Codice articolo locale: BOSSBS-11395R-CY7
Descrizione: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAPs (soluble NSF attachment proteins) and Synaptotagmin. Endobrevin, also designated VAMP-8 or ED, is a 100 amino acid single-pass type IV membrane protein that belongs to the synaptobrevin family. Similar in sequence to the synaptobrevins, endobrevin is abundantly expressed in kidney, moderately expressed in heart and spleen, and slightly expressed in brain, thymus and liver. Endobrevin interacts specifically with the SNAPs, most likely through an endobrevin-containing SNARE complex.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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