Hai cercato: Mass+Spectrometers

Codice catalogo: (SHBT200-26-200UG)

Fornitore: Shenandoah Biotechnology

Codice articolo fornitore: 200-26-200UG

Codice articolo locale: SHBT200-26-200UG

Descrizione: Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

UOM: 1 * 200 µG

Promo

Codice catalogo: (PROOVHG-OSF-PB1000)

Fornitore: LGC Standards PROMOCHEM

Codice articolo fornitore: VHG-OSF-PB1000

Codice articolo locale: PROOVHG-OSF-PB1000

Descrizione: This solution is intended for use as a certified reference material or calibration standard for the analysis of this element in petroleum products or other organic matrices using x-ray fluorescence (XRF) spectrometry, inductively coupled plasma optical emission spectroscopy (ICPOES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.

UOM: 1 * 50 g

Promo

Fornitore: LGC Standards PROMOCHEM

Descrizione: This solution is intended for use as a certified reference material or calibration standard for the analysis of this element in petroleum products or other organic matrices using inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.

Codice catalogo: (BOSSBS-11740R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-11740R-A555

Codice articolo locale: BOSSBS-11740R-A555

Descrizione: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11740R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-11740R-A350

Codice articolo locale: BOSSBS-11740R-A350

Descrizione: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.

UOM: 1 * 100 µl

Promo

Codice catalogo: (SHBT100-37AF-200UG)

Fornitore: Shenandoah Biotechnology

Codice articolo fornitore: 100-37AF-200UG

Codice articolo locale: SHBT100-37AF-200UG

Descrizione: Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

UOM: 1 * 200 µG

Promo

Fornitore: LGC Standards PROMOCHEM

Descrizione: This solution is intended for use as a certified reference material calibration standard for the analysis of these elements in petroleum products or other organic matrices using inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.

Codice catalogo: (PRSI27-767)

Fornitore: ProSci Inc.

Codice articolo fornitore: 27-767

Codice articolo locale: PRSI27-767

Descrizione: Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-0631R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-0631R-FITC

Codice articolo locale: BOSSBS-0631R-FITC

Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].

UOM: 1 * 100 µl

Promo

Codice catalogo: (39116-10MG)

Fornitore: Merck

Codice articolo fornitore: 39116-10MG

Codice articolo locale: SUPL39116-10MG

Descrizione: The tricyclazole CRM may also find the following uses: Determination of tricyclazole content in paddy rice using sliver colloid as a substrate and pyridine as an internal standard by surface-enhanced Raman spectroscopy (SERS). To detect residues of tricyclazole and thiram in pear fruit extracts using SERS. Dissipation studies of penoxsulam tricyclazole and profoxydim in rice paddy systems using HPLC-Diode Array Detection (DAD). Determination of tricyclazole residues in rice using liquid chromatography-tandem mass spectrometry (LC-MS/MS) along with the QuEChERS method of sample preparation. Degradation of tricyclazole (TC) in an aqueous solution and real pesticide industry wastewater (RPW) by electron beam (EB) radiation.

UOM: 1 * 10 mg

Promo

Codice catalogo: (BOSSBS-6770R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-6770R-A647

Codice articolo locale: BOSSBS-6770R-A647

Descrizione: DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) is a novel member of the ser/thr protein kinase family, which mediate apoptosis through their catalytic activities. The full-length cDNA encodes a deduced 414-amino acid protein with a molecular mass of 46.56 kD. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. DRAK1 messenger RNA appears to be ubiquitously expressed in human tissues. Overexpression of DRAK1 induces apoptosis. It has been shown in vitro that DRAK1 is capable of autophosphorylation and of phosphorylating the myosin light chain as an exogenous substrate, and that the noncatalytic C terminus is crucial for full kinase activity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6770R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6770R-CY5.5

Codice articolo locale: BOSSBS-6770R-CY5.5

Descrizione: DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) is a novel member of the ser/thr protein kinase family, which mediate apoptosis through their catalytic activities. The full-length cDNA encodes a deduced 414-amino acid protein with a molecular mass of 46.56 kD. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. DRAK1 messenger RNA appears to be ubiquitously expressed in human tissues. Overexpression of DRAK1 induces apoptosis. It has been shown in vitro that DRAK1 is capable of autophosphorylation and of phosphorylating the myosin light chain as an exogenous substrate, and that the noncatalytic C terminus is crucial for full kinase activity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13356R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-13356R-A350

Codice articolo locale: BOSSBS-13356R-A350

Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13356R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-13356R-FITC

Codice articolo locale: BOSSBS-13356R-FITC

Descrizione: GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENM-011-100)

Fornitore: Biosensis

Codice articolo fornitore: M-011-100

Codice articolo locale: BSENM-011-100

Descrizione: Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) due to its molecular mass and its ability to bind at low affinity not only NGF (see 162030), but also other neurotrophins, including brain-derived neurotrophic factor (BDNF; 113505), neurotrophin-3 (NTF3; 162660), and neurotrophin-4/5 (NTF5; 162662). At the time of its discovery, NGFR was considered a unique type of protein. Subsequently, however, a large superfamily of tumor necrosis factor receptors were found to share the overall structure of NGFR (4 extracellular ligand-binding, cysteine-rich repeats, or CRs, and signaling through association with, or disassociation from, cytoplasmic interactors). The identification of this superfamily helped elucidate some of the biologic functions of NGFR, including its ultimate involvement in the nuclear factor kappa-B (NFKB; see 164011) and apoptosis pathways. As a monomer, NGFR binds NGF with low affinity. Higher affinity binding is achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1; 191315), TRKB (NTRK2; 600456), and TRKC (NTRK3; 191316). TRKA, TRKB, and TRKC are specific for or 'preferred by' NGF, NTF5 and BDNF, and NTF3, respectively (Ip et al., 1993). NTF3 also binds to TRKA and TRKB, but with significantly lower affinity

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI28-512)

Fornitore: ProSci Inc.

Codice articolo fornitore: 28-512

Codice articolo locale: PRSI28-512

Descrizione: ANXA1 encodes a protein that belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

UOM: 1 * 100 µG

Promo