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Codice catalogo: (PRSI76-885)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-885
Codice articolo locale: PRSI76-885
Descrizione: The P1H12 monoclonal antibody reacts with CD146, 118 kDa transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
UOM: 1 * 100 Tests


Codice catalogo: (BOSSBS-0631R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R-A555
Codice articolo locale: BOSSBS-0631R-A555
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11740R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11740R-A680
Codice articolo locale: BOSSBS-11740R-A680
Descrizione: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. localised to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
UOM: 1 * 100 µl


Codice catalogo: (CAYM10011263-100)
Fornitore: Cayman Chemical
Codice articolo fornitore: 10011263-100
Codice articolo locale: CAYM10011263-100
Descrizione: Two types of 15-lipoxygenase (15-LO) have been discovered and characterised, both of which metabolise arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of approximately 76 kDa and exhibits approximately 40% identity to the reticulocyte 15-LO-1.2,3 expression of 15-LO-2 appears to be restricted to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues.
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-0631R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R-A647
Codice articolo locale: BOSSBS-0631R-A647
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11740R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11740R-A647
Codice articolo locale: BOSSBS-11740R-A647
Descrizione: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0631R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R-CY3
Codice articolo locale: BOSSBS-0631R-CY3
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0631R)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R
Codice articolo locale: BOSSBS-0631R
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Codice catalogo: (PRSI28-762)
Fornitore: ProSci Inc.
Codice articolo fornitore: 28-762
Codice articolo locale: PRSI28-762
Descrizione: FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.
UOM: 1 * 50 µG


Codice catalogo: (BOSSBS-0631R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R-A350
Codice articolo locale: BOSSBS-0631R-A350
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Fornitore: LGC Standards PROMOCHEM
Descrizione: The solutions are intended for use as a certified reference material or calibration standard for the analysis of these elements in petroleum products or other organic matrices using inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.

Codice catalogo: (BSENM-017-100-FT)
Fornitore: Biosensis
Codice articolo fornitore: M-017-100-FT
Codice articolo locale: BSENM-017-100-FT
Descrizione: Nerve growth factor receptor (NGFR) is also referred to as p75(NTR) due to its molecular mass and its ability to bind at low affinity not only NGF (see 162030), but also other neurotrophins, including brain-derived neurotrophic factor (BDNF; 113505), neurotrophin-3 (NTF3; 162660), and neurotrophin-4/5 (NTF5; 162662). At the time of its discovery, NGFR was considered a unique type of protein. Subsequently, however, a large superfamily of tumor necrosis factor receptors were found to share the overall structure of NGFR (4 extracellular ligand-binding, cysteine-rich repeats, or CRs, and signaling through association with, or disassociation from, cytoplasmic interactors). The identification of this superfamily helped elucidate some of the biologic functions of NGFR, including its ultimate involvement in the nuclear factor kappa-B (NFKB; see 164011) and apoptosis pathways. As a monomer, NGFR binds NGF with low affinity. Higher affinity binding is achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1; 191315), TRKB (NTRK2; 600456), and TRKC (NTRK3; 191316). TRKA, TRKB, and TRKC are specific for or 'preferred by' NGF, NTF5 and BDNF, and NTF3, respectively. NTF3 also binds to TRKA and TRKB, but with significantly lower affinity.
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-11740R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-11740R-A488
Codice articolo locale: BOSSBS-11740R-A488
Descrizione: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0631R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-0631R-A488
Codice articolo locale: BOSSBS-0631R-A488
Descrizione: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UOM: 1 * 100 µl


Codice catalogo: (PROOVHG-OSF-PB1000)
Fornitore: LGC Standards PROMOCHEM
Codice articolo fornitore: VHG-OSF-PB1000
Codice articolo locale: PROOVHG-OSF-PB1000
Descrizione: This solution is intended for use as a certified reference material or calibration standard for the analysis of this element in petroleum products or other organic matrices using x-ray fluorescence (XRF) spectrometry, inductively coupled plasma optical emission spectroscopy (ICPOES), inductively coupled plasma mass spectrometry (ICP-MS), rotating disc electrode atomic emission spectroscopy (RDE-AES), flame or furnace atomic absorption spectroscopy (AA or GFAA), and other techniques for elemental analysis.
UOM: 1 * 50 g


Codice catalogo: (SHBT200-26-200UG)
Fornitore: Shenandoah Biotechnology
Codice articolo fornitore: 200-26-200UG
Codice articolo locale: SHBT200-26-200UG
Descrizione: Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.
UOM: 1 * 200 µG


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