Hai cercato: C6+NBD-Ceramide

Codice catalogo: (BOSSBS-13297R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-13297R-HRP

Codice articolo locale: BOSSBS-13297R-HRP

Descrizione: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13297R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-13297R-FITC

Codice articolo locale: BOSSBS-13297R-FITC

Descrizione: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13297R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-13297R-A488

Codice articolo locale: BOSSBS-13297R-A488

Descrizione: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5077R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-5077R-CY5.5

Codice articolo locale: BOSSBS-5077R-CY5.5

Descrizione: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4127R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-4127R-HRP

Codice articolo locale: BOSSBS-4127R-HRP

Descrizione: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA = PA >C-1-P >S-1-P. May be involved in cell adhesion and in cell-cell interactions.

UOM: 1 * 100 µl

Promo

Codice catalogo: (USBIC2778-22)

Fornitore: US Biological

Codice articolo fornitore: C2778-22

Codice articolo locale: USBIC2778-22

Descrizione: Anti-CERK Rabbit polyclonal antibody

UOM: 1 * 50 µG

Promo

Codice catalogo: (BOSSBS-13297R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-13297R-CY7

Codice articolo locale: BOSSBS-13297R-CY7

Descrizione: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

UOM: 1 * 100 µl

Promo

Fornitore: Abcam

Descrizione: Anti-C6 Rabbit Monoclonal Antibody [clone: EPR20618-191]

Codice catalogo: (BOSSBS-6318R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-6318R-A680

Codice articolo locale: BOSSBS-6318R-A680

Descrizione: Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.Involvement in disease: Defects in SMPD1 are the cause of Niemann-Pick disease type A (NPDA) ; also known as Niemann-Pick disease classical infantile form. It is an early-onset lysosomal storage disorder caused by failure to hydrolyze sphingomyelin to ceramide. It results in the accumulation of sphingomyelin and other metabolically related lipids in reticuloendothelial and other cell types throughout the body, leading to cell death. Niemann-Pick disease type A is a primarily neurodegenerative disorder characterised by onset within the first year of life, mental retardation, digestive disorders, failure to thrive, major hepatosplenomegaly, and severe neurologic symptoms. The severe neurological disorders and pulmonary infections lead to an early death, often around the age of four. Clinical features are variable. A phenotypic continuum exists between type A (basic neurovisceral) and type B (purely visceral) forms of Niemann-Pick disease, and the intermediate types encompass a cluster of variants combining clinical features of both types A and B.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6318R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-6318R-A647

Codice articolo locale: BOSSBS-6318R-A647

Descrizione: Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.Involvement in disease: Defects in SMPD1 are the cause of Niemann-Pick disease type A (NPDA) ; also known as Niemann-Pick disease classical infantile form. It is an early-onset lysosomal storage disorder caused by failure to hydrolyze sphingomyelin to ceramide. It results in the accumulation of sphingomyelin and other metabolically related lipids in reticuloendothelial and other cell types throughout the body, leading to cell death. Niemann-Pick disease type A is a primarily neurodegenerative disorder characterized by onset within the first year of life, mental retardation, digestive disorders, failure to thrive, major hepatosplenomegaly, and severe neurologic symptoms. The severe neurological disorders and pulmonary infections lead to an early death, often around the age of four. Clinical features are variable. A phenotypic continuum exists between type A (basic neurovisceral) and type B (purely visceral) forms of Niemann-Pick disease, and the intermediate types encompass a cluster of variants combining clinical features of both types A and B.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6318R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-6318R-A555

Codice articolo locale: BOSSBS-6318R-A555

Descrizione: Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.Involvement in disease: Defects in SMPD1 are the cause of Niemann-Pick disease type A (NPDA) ; also known as Niemann-Pick disease classical infantile form. It is an early-onset lysosomal storage disorder caused by failure to hydrolyze sphingomyelin to ceramide. It results in the accumulation of sphingomyelin and other metabolically related lipids in reticuloendothelial and other cell types throughout the body, leading to cell death. Niemann-Pick disease type A is a primarily neurodegenerative disorder characterized by onset within the first year of life, mental retardation, digestive disorders, failure to thrive, major hepatosplenomegaly, and severe neurologic symptoms. The severe neurological disorders and pulmonary infections lead to an early death, often around the age of four. Clinical features are variable. A phenotypic continuum exists between type A (basic neurovisceral) and type B (purely visceral) forms of Niemann-Pick disease, and the intermediate types encompass a cluster of variants combining clinical features of both types A and B.

UOM: 1 * 100 µl

Promo

Codice catalogo: (99435.260)

Fornitore: VWR Chemicals

Codice articolo locale: VWRC99435.260

Descrizione: Flow Cup viscosity standards are specifically formulated for use with viscosity flow cups such as Ford, Shell and Zahn.

UOM: 1 * 500 mL

MSDS Certificati Promo

Codice catalogo: (BOSSBS-5077R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-5077R-FITC

Codice articolo locale: BOSSBS-5077R-FITC

Descrizione: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5077R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-5077R-CY7

Codice articolo locale: BOSSBS-5077R-CY7

Descrizione: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5077R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-5077R-CY3

Codice articolo locale: BOSSBS-5077R-CY3

Descrizione: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

UOM: 1 * 100 µl

Promo

Fornitore: Thermo Fisher Scientific

Descrizione: Hexanal ≥98%

MSDS Certificati