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Codice catalogo: (BOSSBS-2358R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-2358R-A680
Codice articolo locale: BOSSBS-2358R-A680
Descrizione: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Fornitore: ENZO LIFE SCIENCES
Descrizione: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

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Codice catalogo: (1.17179.0001)
Fornitore: Merck
Codice articolo fornitore: 1.17179.0001
Codice articolo locale: MERC1.17179.0001
Descrizione: Carbon dioxide is an important parameter for the assessment of the surface water quality and of the corrosive behavior of water. The kit is used for water and wastewater treatments following titrimetric method.
UOM: 1 * 1 pezzi


Codice catalogo: (1.11148.0001)
Fornitore: Merck
Codice articolo fornitore: 1.11148.0001
Codice articolo locale: MERC1.11148.0001
Descrizione: MQuant® titrimetric and colorimetric methods.
UOM: 1 * 200 Tests

Codice catalogo: (BOSSBS-2358R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-2358R-CY3
Codice articolo locale: BOSSBS-2358R-CY3
Descrizione: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2358R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-2358R-A555
Codice articolo locale: BOSSBS-2358R-A555
Descrizione: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Codice catalogo: (1.01603.0001)
Fornitore: Merck
Codice articolo fornitore: 1.01603.0001
Codice articolo locale: MERC1.01603.0001
Descrizione: Phenol-free staining kit for the Gram staining method
UOM: 1 * 1 SET

Codice catalogo: (1.10307.0500)
Fornitore: Merck
Codice articolo fornitore: 1.10307.0500
Codice articolo locale: MERC1.10307.0500
Descrizione: Test kit, Proteina (metodo Biuret a 546 nm), soluzione reagente per circa 250 determinazioni
UOM: 1 * 500 mL

Codice catalogo: (MDT100-1KT)
Fornitore: SIGMA ALDRICH MICROSCOPY
Codice articolo fornitore: MDT100-1KT
Codice articolo locale: SIAMMDT100-1KT
Descrizione: Designed for orientation of excised surgical specimens. This method of permanently marking the margins of tissue specimens is very beneficial to surgeon and pathologists testing for skin cancer.
UOM: 1 * 1 KIT


Codice catalogo: (BOSSBS-8634R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-8634R-HRP
Codice articolo locale: BOSSBS-8634R-HRP
Descrizione: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
UOM: 1 * 100 µl


Codice catalogo: (1.11142.0001)
Fornitore: Merck
Codice articolo fornitore: 1.11142.0001
Codice articolo locale: MERC1.11142.0001
Descrizione: MQuant® titrimetric and colorimetric methods.
UOM: 1 * 400 Tests

Fornitore: Merck
Descrizione: Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.

Codice catalogo: (1.15973.0002)
Fornitore: Merck
Codice articolo fornitore: 1.15973.0002
Codice articolo locale: MERC1.15973.0002
Descrizione: Nuclear staining in connective tissue staining methods
UOM: 1 * 2 pezzi

MSDS


Codice catalogo: (A-054-3X1.2ML)
Fornitore: Merck
Codice articolo fornitore: A-054-3X1.2ML
Codice articolo locale: SUPLA-054-3X1.2ML
Descrizione: Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.
UOM: 1 * 3 pezzi

Certificati


Codice catalogo: (ENZOBMLKI1770005)
Fornitore: ENZO LIFE SCIENCES
Codice articolo fornitore: BMLKI1770005
Codice articolo locale: ENZOBMLKI1770005
Descrizione: Fluor de Lys®-SIRT1 is a fluorogenic, acetylated peptide substrate for SIRT1 (human Sirtuin 1). Based on residues 379-382 of p53 (Arg-His-Lys-Lys(Ac)), a site of regulatory acetylation by the p300 and CBP acetyltransferases (lysines 381, 382), it was the best substrate for SIRT1 from among a panel of substrates patterned on p53, histone H3, and histone H4 acetylation sites. Fluor de Lys®-SIRT1 is deacetylated by SIRT1 (BML-SE239) at a rate of more then 8-fold that of the acetylated lysine substrate, Fluor de Lys® (Prod. No. BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD+). The Km of Fluor de Lys®-SIRT1 for human recombinant Sirtuin 1 is 108 µM (determined at 37°C, 500 µM NAD+). Must be used in conjunction with Fluor de Lys® Developer II (Prod. No. BML-KI176). Fluorescent signal indicates deacetylation of Lys382. Sufficient for 100-200 assays of human recombinant SIRT1 (1U/well, 50-100 µM substrate).
UOM: 1 * 1 Vial

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Fornitore: LGC Standards PROMOCHEM
Descrizione: This standard reference material is intended to facilitate the development of chemical methods of analysis for trace elements.

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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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