Hai cercato: 2\'-Deoxy-2\'-fluorouridine

Fornitore: Apollo Scientific

Descrizione: 2'-Deoxy-2'-fluorouridine 98%

Fornitore: Thermo Scientific

Descrizione: 2'-Deoxy-2'-fluorouridine 97%

MSDS

Fornitore: TCI EUROPE

Descrizione: 2'-Deoxy-2'-fluorouridine ≥97.0% (by HPLC)

Codice catalogo: (APOSBIMN2019-1G)

Fornitore: Apollo Scientific

Codice articolo fornitore: BIMN2019-1G

Codice articolo locale: APOSBIMN2019-1G

Descrizione: 2’-Deoxy-2’-fluorouridine-3’-CE-phosphoramidite ≥95%

UOM: 1 * 1 g

Promo

Fornitore: Thermo Scientific

Descrizione: 5-Fluoro-5'-deoxyuridine (Doxifluridine)

Fornitore: Apollo Scientific

Descrizione: (+)-5-Fluoro-5'-deoxyuridine

Fornitore: TCI EUROPE

Descrizione: 5-Fluoro-5'-deoxyuridine (Doxifluridine) ≥98.0% (by HPLC, titration analysis)

Fornitore: Thermo Scientific

Descrizione: 2'-Deoxy-2'-fluorouridine 97%

MSDS Certificati

Codice catalogo: (J64217.06)

Fornitore: Thermo Scientific

Codice articolo fornitore: J64217.06

Codice articolo locale: ALFAJ64217.06

Descrizione: 5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyuridine 98%

UOM: 1 * 5 g

MSDS Certificati Promo

Codice catalogo: (PRSI33-744)

Fornitore: ProSci Inc.

Codice articolo fornitore: 33-744

Codice articolo locale: PRSI33-744

Descrizione: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

UOM: 1 * 100 µG

New Product Promo

Codice catalogo: (PRSI33-768)

Fornitore: ProSci Inc.

Codice articolo fornitore: 33-768

Codice articolo locale: PRSI33-768

Descrizione: Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.

UOM: 1 * 100 µG

New Product Promo

Fornitore: Apollo Scientific

Descrizione: 5-Fluorouridine 97%

Fornitore: TCI EUROPE

Descrizione: 5-Fluorouridine ≥98.0% (by titrimetric analysis)

Fornitore: Thermo Scientific

Descrizione: 5-Fluorouridine ≥97%

MSDS Certificati

Codice catalogo: (PRSIXW-8050)

Fornitore: ProSci Inc.

Codice articolo fornitore: XW-8050

Codice articolo locale: PRSIXW-8050

Descrizione: FUNCTION: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI55-545)

Fornitore: ProSci Inc.

Codice articolo fornitore: 55-545

Codice articolo locale: PRSI55-545

Descrizione: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

UOM: 1 * 400 µl

New Product Promo