Human recombinant TGF-alpha (from E. coli)
Fornitore: Shenandoah Biotechnology
Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein, containing 50 amino acids
- Functions as a mitogen to activate epithelial cell proliferation, growth and differentiation
TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier's disease.
It is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.
Informazioni per l'ordine: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Attenzione: This product is for research use only and is not for use in humans.
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