Mouse recombinant G-CSF (from E. coli)
Fornitore: Shenandoah Biotechnology
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation.
- Produced from genetically modified E. coli
- Promotes neurogenesis and inhibits neuronal apoptosis
- Human and mouse G-CSF proteins are cross-reactive
- Contains 179 amino acid
G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNFα), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways.
Informazioni per l'ordine: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Attenzione: This product is for research use only and is not for use in humans.
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