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Anti-p95 NBS1 Ser343 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Fornitore: Bioss
BS-6125R-A680
BOSSBS-6125R-A680EA 921 EUR
BOSSBS-6125R-A680
Anti-p95 NBS1 Ser343 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anticorpi
Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-More Product Information
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