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Anti-FOXO1 Rabbit Polyclonal Antibody (Cy7®)

Fornitore: Bioss
BS-2537R-CY7
BOSSBS-2537R-CY7EA 900 EUR
BOSSBS-2537R-CY7
Anti-FOXO1 Rabbit Polyclonal Antibody (Cy7®)
Anticorpi
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasingMore Product Information
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