Hai cercato: ProSci Inc.

Codice catalogo: (PRSI43-043)

Fornitore: ProSci Inc.

Codice articolo fornitore: 43-043

Codice articolo locale: PRSI43-043

Descrizione: Anti-STRA8 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSIXP-5183)

Fornitore: ProSci Inc.

Codice articolo fornitore: XP-5183

Codice articolo locale: PRSIXP-5183

Descrizione: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI31-115)

Fornitore: ProSci Inc.

Codice articolo fornitore: 31-115

Codice articolo locale: PRSI31-115

Descrizione: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with g proteins that activate a phosphatidylinositol. calcium second messenger system.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI31-130)

Fornitore: ProSci Inc.

Codice articolo fornitore: 31-130

Codice articolo locale: PRSI31-130

Descrizione: The 5-HT1F receptor is present in both human vascular and neuronal tissue. This gene is localized at 3p12.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI31-125)

Fornitore: ProSci Inc.

Codice articolo fornitore: 31-125

Codice articolo locale: PRSI31-125

Descrizione: APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI43-026)

Fornitore: ProSci Inc.

Codice articolo fornitore: 43-026

Codice articolo locale: PRSI43-026

Descrizione: Anti-Trp63 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI43-031)

Fornitore: ProSci Inc.

Codice articolo fornitore: 43-031

Codice articolo locale: PRSI43-031

Descrizione: Anti-PLEKHA5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI43-030)

Fornitore: ProSci Inc.

Codice articolo fornitore: 43-030

Codice articolo locale: PRSI43-030

Descrizione: Anti-USP6 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI45-518)

Fornitore: ProSci Inc.

Codice articolo fornitore: 45-518

Codice articolo locale: PRSI45-518

Descrizione: Anti-UBR5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI45-515)

Fornitore: ProSci Inc.

Codice articolo fornitore: 45-515

Codice articolo locale: PRSI45-515

Descrizione: Anti-EBAG9 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSIXP-5190BT)

Fornitore: ProSci Inc.

Codice articolo fornitore: XP-5190BT

Codice articolo locale: PRSIXP-5190BT

Descrizione: Anti-IL4 Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSIXP-5197)

Fornitore: ProSci Inc.

Codice articolo fornitore: XP-5197

Codice articolo locale: PRSIXP-5197

Descrizione: Iterleukin 7 is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL-7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL-7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL-7 stimulates the proliferation of CD4+/CD8+ cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI30-388)

Fornitore: ProSci Inc.

Codice articolo fornitore: 30-388

Codice articolo locale: PRSI30-388

Descrizione: ALDOC gene is a member of the class I fructose-biphosphate aldolase gene family. ALDOC is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI36-170)

Fornitore: ProSci Inc.

Codice articolo fornitore: 36-170

Codice articolo locale: PRSI36-170

Descrizione: VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI36-175)

Fornitore: ProSci Inc.

Codice articolo fornitore: 36-175

Codice articolo locale: PRSI36-175

Descrizione: Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome, mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI36-180)

Fornitore: ProSci Inc.

Codice articolo fornitore: 36-180

Codice articolo locale: PRSI36-180

Descrizione: Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the DD-containing adaptor molecule FADD, procaspase-8, procaspase-10 and c-FLIP. The DISC structure provides a platform for the oligomerization of procaspase-8 that allows two procaspase-8 homodimers to be in the close proximity leading to the initial activation of procaspase-8. At the first cleavage step, the N-terminal p43/p41 and the C-terminal p30 cleavage products are generated. Importantly, these cleavage products already possess catalytic activity. At the second cleavage step, p43/p41 and p30 are processed to p10 and p20, respectively, which leads to the generation of the active caspase-8 heterotetramer (p20/p10)2.

UOM: 1 * 100 µG

Promo