Hai cercato: MP Biomedicals

Fornitore: MP Biomedicals

Descrizione: Cholesterol is a component used for the preparation and study of artificial model membranes. One example is a study of valinomycin induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions. Positively charged cyanine dyes were used that fluorimetrically respond to the change in potential. Cholesterol is suitable for use in liposome preparations. It is standard for clinical work.

Fornitore: MP Biomedicals

Descrizione: L-Malic Acid is a dicarboxylic acid that is made by all living organisms. The malate anion is an intermediate in the citric acid cycle.

Fornitore: MP Biomedicals

Descrizione: Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen, or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds. PEG is incompatible with phenol and may reduce the antimicrobial action of other preservatives.

MSDS

Fornitore: MP Biomedicals

Descrizione: Polyethylenimine is a branched chain polymer having a ratio of 1:2:1 of primary:secondary:tertiary amines with a branching site every 3 to 3,5 nitrogen atoms and a base structure of (CH₂CH₂NH)x. The nitrogen atoms must be protonated to achieve cationic charge, so the cationic charge density is pH dependent.

MSDS

Codice catalogo: (ICNA0202071)

Fornitore: MP Biomedicals

Codice articolo fornitore: 0202071

Codice articolo locale: ICNA0202071

Descrizione: Mean Pore Size: 60Å
Particle Size: 32-63 µm

UOM: 1 * 25 kg

Promo

Fornitore: MP Biomedicals

Descrizione: o-Nitrophenyl-β-D-galactoside is a cell culture component for molecular genetics. It is chromogenic substrate for b-galactosidase and hence is useful in the detection of lacZ activity.

Fornitore: MP Biomedicals

Descrizione: Protamine sulphate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having much basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes protamine takes the form of nucleoprotamine linked with DNA.

Fornitore: MP Biomedicals

Descrizione: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.

Fornitore: MP Biomedicals

Descrizione: Used for studies of pharmacological activity including: synergism with fluconazole against <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>, efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome, nutrient-sensitised screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis,drug effects viewed from a signal transduction network perspective, enhanced cytotoxic effect of proteasome inhibitor MG132, mechanism of action on phasic smooth muscles.

Fornitore: MP Biomedicals

Descrizione: Applications
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. It is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA.
Product Description
The crystal structure of Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds,it is a strong chaotropic agent.Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a freeflowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical

Grade: Ultra Pure
Purity: >99%
Keywords: Guanidium chloride, chaotropic agent
Key Applications: Chaeotropic agent
Product Type: Biochemicals
Biochemical Category: Chaotropic Agents
Density: 1.345 g/cm³ at 20 °C (Lit.)
Melting Point: 180-190 °C
UV/Visible Absorbance: OD260nm (6.0 M aq soln) <0.03
Presentation: White Crystalline Powder
pH: 4-6 (6.0 M aq soln)
Solubility: Soluble in water,Clear, Colorless Solution (6 M - clear, colorless solution).
Storage & Handling: Room Temperature, desiccate

MSDS

Fornitore: MP Biomedicals

Descrizione: Easily soluble in water. The aqueous solution is unstable and can be used only for a few days even if it is kept in a refrigerator. 1% aqueous solution is dark and turns reddish when exposed to light.

Fornitore: MP Biomedicals

Descrizione: Ammonium Sulfate may be used for the precipitation or fractionation of proteins or for purification of antibodies.

Fornitore: MP Biomedicals

Descrizione: Pig Diaphorase (from Heart)

Fornitore: MP Biomedicals

Descrizione: (-)-trans-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils.

Fornitore: MP Biomedicals

Descrizione: Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Other uses for poly-lysine have been reported as well:
• Conjugation to methotrexate for increased drug transport.
• Microencapsulation of islets.
• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.
• Immobilation of living cells in biocompatible semipermeable microcapsules.
• In the preparation of polycationic beads.
• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Fornitore: MP Biomedicals

Descrizione: β-Alanine is an N-blocked form of alanine. A nonselective endogenous glycine receptor agonist; a taurine analogue; an electrolyte.