Hai cercato: Biosensis

Codice catalogo: (BSENR-173-500)

Fornitore: Biosensis

Codice articolo fornitore: R-173-500

Codice articolo locale: BSENR-173-500

Descrizione: Arc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. Arg3.1 expression is detectable in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus, hypothalamus, amygdala.

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENR-1313-100)

Fornitore: Biosensis

Codice articolo fornitore: R-1313-100

Codice articolo locale: BSENR-1313-100

Descrizione: Maltose binding protein (MBP) is encoded by the malE gene of E.coli. MBP is often used in protein expression studies because it creates a stable fusion product that does not appear to interfere with the bioactivity of the protein of interest. It also allows for its easy purification from bacterial extracts under mild conditions.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENR-099-500)

Fornitore: Biosensis

Codice articolo fornitore: R-099-500

Codice articolo locale: BSENR-099-500

Descrizione: FUNCTION: Seems to promotes the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENM-1314-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1314-100

Codice articolo locale: BSENM-1314-100

Descrizione: The Myc tag contains the amino acids Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu (E-Q-K-L-I-S-E-E-D-L) corresponding to amino acids 410-419 of human Myc. This tag is widely used for monitoring expression of recombinant proteins in bacteria, insect and mammalian cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1573-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1573-100

Codice articolo locale: BSENM-1573-100

Descrizione: Protein DJ-1 has many roles including protecting cells against oxidative stress and cell death (Ref: SwissProt). Mutations in the DJ-1 gene have been associated with rare forms of autosomal recessive early-onset Parkinson's disease.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1531-100)

Fornitore: Biosensis

Codice articolo fornitore: C-1531-100

Codice articolo locale: BSENC-1531-100

Descrizione: FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity. SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum. Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. SIMILARITY: Belongs to the orexin family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENM-1572-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1572-100

Codice articolo locale: BSENM-1572-100

Descrizione: 14.3.3 protein eta or 14.3.3  binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (Ref SwissProt). 14.3.3 protein eta is widely expressed as both homodimers and heterodimers and are concentrated in the nervous system. High concentrations of 14.3.3 protein eta have been linked to Creutzfeld Jacob Disease, Parkinson's Disease and early-onset schizopherenia.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1409-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1409-50

Codice articolo locale: BSENC-1409-50

Descrizione: Vimentins are class-III intermediate filaments specific to mesenchymal tissue. Vimentin is an important cytoskeletal component responsible for maintaining cell integrity and has a probable role in the intracellular transport of proteins such as lipoproteins between the nucleus and plasma membrane. Immunohistochemical staining for Vimentin is characteristic of sarcomas. 

UOM: 1 * 50 µl

Promo

Codice catalogo: (BSENM-1391-50)

Fornitore: Biosensis

Codice articolo fornitore: M-1391-50

Codice articolo locale: BSENM-1391-50

Descrizione: Neurofilaments are composed of three intermediate filament proteins: light (~68 kDa), medium (~160 kDa) and heavy (~200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament light (NF68 or NF-L) is the most abundant of the three proteins.

UOM: 1 * 50 µl

Promo

Codice catalogo: (BSENM-1325-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1325-100

Codice articolo locale: BSENM-1325-100

Descrizione: Clone OX-42 recognises the rat equivalent of human CD11b. CD11b is a single-pass type I membrane protein that belongs to the integrin alpha chain family. CD11b is predominantly expressed in monocytes and granulocytes and is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles (Ref: SWISSPROT). CD11b is also frequently used as a microglial marker allowing to distinguish between quiescent and activated microglia based on the intensity of CD11b staining.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1376-250)

Fornitore: Biosensis

Codice articolo fornitore: M-1376-250

Codice articolo locale: BSENM-1376-250

Descrizione: Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. GAPDH may have other roles in the activation of transcription and in the regulation of apoptosis as well as Alzheimer's disease and Huntington's disease. The immunogen used to raise this particular antibody was extensively purified pig GAPDH. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue.

UOM: 1 * 250 µl

Promo

Codice catalogo: (BSENS-051-50)

Fornitore: Biosensis

Codice articolo fornitore: S-051-50

Codice articolo locale: BSENS-051-50

Descrizione: FUNCTION: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SUBUNIT: Homodimer, associated by noncovalent forces. SUBCELLULAR LOCATION: Secreted protein. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 50 µG

Promo

Codice catalogo: (BSENR-1683-500)

Fornitore: Biosensis

Codice articolo fornitore: R-1683-500

Codice articolo locale: BSENR-1683-500

Descrizione: Beta-synuclein is a soluble cytoplasmic protein associated with synaptic vesicles and a member of the synuclein family. Mutations in alpha-synuclein cause early onset Parkinson's disease. Expression of beta synuclein may modulate alpha-synuclein aggregation found in Parkinson's disease.

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENR-1621-100)

Fornitore: Biosensis

Codice articolo fornitore: R-1621-100

Codice articolo locale: BSENR-1621-100

Descrizione: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENR-1680-500)

Fornitore: Biosensis

Codice articolo fornitore: R-1680-500

Codice articolo locale: BSENR-1680-500

Descrizione: Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENR-1547-100)

Fornitore: Biosensis

Codice articolo fornitore: R-1547-100

Codice articolo locale: BSENR-1547-100

Descrizione: Lysine acetylation of histones and non-histone proteins plays an important part in many cellular processes such as chromatin and nuclear signaling, transcription, gene silencing, cell cycle progression, apoptosis, differentiation, DNA replication and repair.

UOM: 1 * 100 µl

Promo